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ProteomicsSalmonella Typhimurium effector SseI regulates host peroxisomal dynamics to acquire lysosomal cholesterol for better intracellular growth
Intracellular Salmonella resides and multiplies in cholesterol-rich specialized compartment called Salmonella-containing vacuoles (SCVs) and avoids fusion with acidic lysosomes. Given, lysosomes are primary organelle that redistributes LDL derived cholesterol to other organelles; we questioned how l...
ORGANISM(S): Homo sapiens (Human) 
2024-10-28 | PXD055151 | Pride
Salmonella typhimurium Cholesterol Arf1 activation Peroxisome targeting sequence Peroxisomes 
TranscriptomicsWTS of breast cancer samples
Whole transcriptome sequencing was performed on tumors collected from patients before and after hydroxyprogesterone exposure and controls. By comparing the gene expression patterns in exposed and unexposed groups, we aim to understand the molecular basis of action of hydroxyprogesterone on primary b...
ORGANISM(S): Homo sapiens 
2024-02-10 | E-MTAB-11412 | biostudies-arrayexpress
TranscriptomicsA single functional blast resistance gene Pi54 activates complex defense mechanism in Rice
To investigate the responses of resistance gene Pi54 at transcriptome level in blast resistant transgenic rice line TP-Pi54 during infection by Magnaporthe oryzae, we studied the co-expression analysis using microarray along with susceptible non-transgenic line Taipei 309 (TP). Suitable controls ...
ORGANISM(S): Oryza sativa Japonica Group 
2011-12-08 | E-GEOD-28308 | biostudies-arrayexpress
TranscriptomicsA 7-month inhalation toxicology study in C57BL/6 mice demonstrates reduced pulmonary inflammation and emphysema following smoking cessation or switching to e-vapor products.
Cigarette smoking causes serious diseases, including lung cancer, heart disease, and emphysema. While cessation remains the most effective approach to minimize smoking-related disease, alternative non-combustible tobacco-derived nicotine containing products may reduce disease risks among those unabl...
ORGANISM(S): Mus musculus 
2021-03-18 | E-MTAB-9597 | biostudies-arrayexpress
ProteomicsPfAP2-MRP DNA-binding protein is a master regulator of parasite pathogenesis during malaria parasite blood stages
The pathogenicity of the malaria parasites results from their ability to invade and remodel red blood cells (RBCs), expressing antigenic variant proteins for immune evasion and survival, and then to egress from the host cell. These sequential processes require concerted actions of a large number of...
ORGANISM(S): Plasmodium falciparum 
2024-01-26 | PXD030308 | Pride
Egress Var Apiap2 P.falciparum Epigenetics Invasion 
UnknownAntitumor Activity of Pembrolizumab in Biomarker-Unselected Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma: Results From the Phase Ib KEYNOTE-012 Expansion Cohort.
Not available
S-EPMC6804896 | biostudies-literature
UnknownAssociation of SUMOylation Pathway Genes With Stroke in a Genome-Wide Association Study in India.
Not available
S-EPMC8362360 | biostudies-literature
UnknownQuality-adjusted time without symptoms of disease or toxicity and quality-adjusted progression-free survival with niraparib maintenance in first-line ovarian cancer in the PRIMA trial.
Not available
S-EPMC9511290 | biostudies-literature
TranscriptomicsTranscription profiling of Basmati T-DNA insertional mutant lines
The aim of this study was to look for the changes at the transcriptome level caused by the same T-DNA cassette in three mutants of Basmati 370 with different phenotypes. The comparative analysis of differentially expressed genes was conducted individually and collectively for all three mutants. RNA ...
ORGANISM(S): Oryza sativa Indica Group 
2013-12-31 | E-GEOD-31248 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wild type Basmati 370 and its T-DNA insertional mutant OsAPC6.
The aim of this study was to look for the changes at the transcriptome level caused by the insertion of a T-DNA in mutant of Basmati 370 with dwarf phenotype. The comparative analysis of differentially expressed genes was conducted individually and collectively for both. RNA from wild type Basmati ...
ORGANISM(S): Oryza sativa Indica Group 
2013-12-31 | E-GEOD-31200 | biostudies-arrayexpress
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