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Bulk RNA-seq data for Trex1 WT and KO mice from the heart. Used for manuscript in submission at Science Advances.
ORGANISM(S): Mus musculus 
Using a CRISPR/Cas9-based approach, we engineered human primary CD4+ T cells in which the bait protein SLP76 was tagged with an affinity Twin-Strep-tag (OST). Through affinity purification coupled with quantitative mass spectrometry, this system allows determining the composition and dynamics of the...
ORGANISM(S): Homo sapiens (Human) 
2022-01-28 | PXD028939 | Pride
Using a CRISPR/Cas9-based approach, we engineered human primary CD4+ and CD8+ T cells in which a bait protein (LAT, SLP76, VAV1 or ZAP70) was tagged with an affinity Twin-Strep-tag (OST), with the purpose of determining by quantitative mass spectrometry the composition and dynamics of the signalosom...
ORGANISM(S): Homo sapiens (Human) 
2022-01-10 | PXD024820 | Pride
We hypothesized that mapping genetic variants associated with promoter and enhancer functions can provide novel insights into the mechanism through which eQTLs (expression quantitative trait loci) exert their effects on gene expression. To this end, we quantified genome-wide promoter usage and enhan...
ORGANISM(S): Homo sapiens 
Stress granules (SGs) are transient membraneless organelles protecting yeast and mammalian cells from stress-induced damage, whereas plant SGs remain poorly understood. Recently, we identified Tudor Staphylococcal Nuclease (TSN) as a stable component of Arabidopsis SGs. As a first step to investigat...
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
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