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TranscriptomicsNCI-H1299 cell line transfected with human DENND2D and vector
Gene expression for NCI-H1299 cell line transfected with human DENND2D and vector (pcDNA3.1/V5-His TOPO TA vector) respectively. The microarray experiment was designed to perform four replicates for each H1299-DENND2D and H1299-vector sample. cRNA used in replication 1 and 2 was from the same label...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-16890 | biostudies-arrayexpress
MetabolomicsSearching for Drug Synergy Against Cancer Through Polyamine Metabolism Impairment: Insight Into the Metabolic Effect of Indomethacin on Lung Cancer Cells
Non-small cell lung cancer (NSCLC) is the most lethal and prevalent type of lung cancer. In almost all types of cancer, the levels of polyamines (putrescine, spermidine, and spermine) are increased, playing a pivotal role in tumor proliferation. Indomethacin, a non-steroidal anti-inflammatory drug, ...
2021-02-08 | MTBLS873 | MetaboLights
TranscriptomicsExpression data for cultured NCI-H1299 parental and spheroid cells as well as their derived xenograft models
Current approaches to the preclinical investigation for novel cancer therapies rely heavily on the use of traditional cancer cell lines maintained in serum-containing conditions. The discrepancy between promising preclinical efficacy and clinical outcome of most novel anticancer agents emphasizes a ...
ORGANISM(S): Homo sapiens 
2010-07-30 | E-GEOD-21612 | biostudies-arrayexpress
GenomicsZNF200 RNA-seq in H1299 cell line
ZNF200 RNA-seq in H1299 cell line
PRJNA1322361 | ENA
ProteomicsH1299 Cell Line LC-MSMS plus 29 synthetic peptides corresponding putative UTR peptides
H1299 cell line proteome for searching novel UTR(untranslated region)peptides. This project includes 29 synthetic peptides corresponding putative UTR peptides.
ORGANISM(S): Homo sapiens (Human) 
2019-11-19 | PXD016207 | Pride
Lc-msms H1299 Utr 
TranscriptomicsLentiviral shRNA knockdown of PTK7 in lung adenocarcinoma cell lines NCI-H1299 and NCI-H2009
PTK7 was identified from a meta-analysis of 1905 non-small-cell lung cancer (NSCLC) samples across 12 datasets to be one of seven genes commonly up-regulated in lung adenocarcinoma (ADC). Using ADC cell lines NCI-H1299 and NCI-H2009, disruption of PTK7 resulted in decreased cell viability and induct...
ORGANISM(S): Homo sapiens 
2014-01-01 | E-GEOD-50138 | biostudies-arrayexpress
TranscriptomicsRNA sequencing of non–small cell lung cancer (NSCLC) cell line H1299 following chloroquine (CQ) treatment
Functional lysosomes are essential for tumor growth. CQ, a widely used lysosome inhibitor, has been combined with various other therapeutics for testing in cancer patients. However, no studies have reported enhanced antitumor effects from these treatments. To investigate how tumor cells survive CQ-m...
ORGANISM(S): Homo sapiens 
2025-12-05 | E-MTAB-16126 | biostudies-arrayexpress
TranscriptomicsThe effect on gene expression by p53 family members and the knockdown of AKR1B10
To evaluate the effect on gene expression by p53 family members and AKR1B10, we overexpressed p53 family members in H1299 cells or knocked down AKR1B10 in HCT116 cells and evaluated the gene expression by microarray analysis. Gene expression was measured in H1299 cells infected with adenovirus expre...
ORGANISM(S): Homo sapiens 
2013-10-31 | E-GEOD-47096 | biostudies-arrayexpress
TranscriptomicsCoordinated regulation of MAPK signaling pathway and microRNA in response to ionizing radiation in lung cancer cells
microRNA regulates cellular responses to ionizing radiation (IR) through the translational control of target genes. We analyzed time-series changes in microRNA expressions upon γ-irradiation in H1299 lung cancer cell lines using microarray. Significantly changed microRNAs were selected based on ANOV...
ORGANISM(S): Homo sapiens 
2011-09-13 | E-GEOD-30075 | biostudies-arrayexpress
GenomicsKnockdown LRRK1-CAPT in NCI-H1299 lung cancer cell line
Knockdown LRRK1-CAPT in NCI-H1299 lung cancer cell line
PRJNA912146 | ENA
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