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ProteomicsMouse TAPBPR functions as an MHC-I peptide exchange catalyst
Human TAPBPR is known to function as a Major Histocompatibility Complex class I (MHC-I) peptide exchange catalyst which shapes the peptide repertoire presented to immune cells. Never14theless, investigations characterizing TAPBPR from other species are limited. Here, we characterize mouse TAPBPR, ex...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-23 | PXD069965 | Pride
Mouse Tapbpr Immunopeptidomics Mhc-i Lc-ms/ms 
ProteomicsTCR phosphoproteome using DP thymocytes stimulated by H2-Kb MHC tetramers
Quantitative phosphoproteome with OT-I TAP-/- mice DP thymocytes stimulated by H2-Kb tetramers for 2 min. The quantitative data were calculated by the spike-in standard lysates from DPK cells cultured in the heavy media containing 15N2 13C6-lysine and 15N4 13C6-arginine.
ORGANISM(S): Mus Musculus (mouse) 
2023-07-27 | PXD036851 | JPOST Repository
UnknownDevelopmental Sculpting of Intracortical Circuits by MHC Class I H2-Db and H2-Kb.
Not available
S-EPMC4785944 | biostudies-literature
UnknownMHC class I H2-Kb negatively regulates neural progenitor cell proliferation by inhibiting FGFR signaling.
Not available
S-EPMC8270425 | biostudies-literature
ProteomicsMouse TAPBPR functions as an MHC-I peptide exchange catalyst
Human TAPBPR is known to function as a Major Histocompatibility Complex class I (MHC-I) peptide exchange catalyst which shapes the peptide repertoire presented to immune cells. Never14theless, investigations characterizing TAPBPR from other species are limited. Here, we characterize mouse TAPBPR, ex...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-23 | PXD068540 | Pride
H-2kb Mouse tapbpr Peptide exchange H-2db Mhc-i Calnexin 
TranscriptomicsKaedeGreen and Red CD8 T cells from vaccinia-GP33 infected skin
In order to determine transcriptional differences between cells in the draining lymph node and those recently emigrating from the skin, we performed single cell RNA sequencing on KaedeGreen and KaedeRed CD8 T cells 12 days post infection with vaccinia-GP33. CD8+ cells were MACS enriched. Cells were ...
ORGANISM(S): Mus musculus 
2024-01-30 | GSE241820 | GEO
OtherIdentification of rejection-associated indirect CD4 T cell epitopes provides a target for donor-specific transplant tolerance
Antibody-mediated rejection, caused by antibodies against the donor human leukocyte antigen (HLA) molecules plays a fundamental role in graft rejection in transplantation. Most significant is transplant patients who generate antibodies against the donor HLA-DQ have the highest risk of rejection. In ...
ORGANISM(S): Mus musculus Homo sapiens 
2024-09-17 | GSE277075 | GEO
ProteomicsQuantitative cell type specific immunopeptidome analysis during macrophage and tumor co-evolution reveals therapeutic MHC-I restricted peptides in glioblastoma
Glioblastoma treatment by immunotherapy is limited by the immunosuppresive tumor microenvironment, in part created by GBM associated macrophages. To uncover targetable MHC-I peptides for targeted immunotherapy, we performed cell type specific immunopeptidome analysis on primary macrophages and GBM t...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-03 | PXD057588 | Pride
Tumor associated macrophage Mhc-i restricted peptides Glioblastoma Immunopeptidome 
ProteomicsImmunopeptidome on MC38 Cell line
PTM – driven antigenicity – immunopeptidome of MC38 cell line
ORGANISM(S): Mus musculus (Mouse) 
2022-10-12 | PXD017448 | Pride
Ptm Immunopeptidome 
UnknownSuppression of Non-Random Fertilization by MHC Class I Antigens.
Not available
S-EPMC7699254 | biostudies-literature
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