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TranscriptomicsExpression profiling of wheat heads from spring wheat Chinese Spring (CS) and CS-7EL (CS with additional chromosome arm 7EL from Thinopyrum elongatum), after inoculation with either water (mock inoculation) or Fusarium graminearum
The ditelocentric addition line CS-7EL of the spring wheat (Triticum aestivum) cultivar Chinese Spring (CS) contains the long arm of the chromosome 7E from Thinopyrum elongatum (CS-7EL), which confers high resistance to fusarium head blight. It is of great interest to breeders to integrate the resis...
ORGANISM(S): Triticum aestivum 
2015-09-14 | E-GEOD-70797 | biostudies-arrayexpress
TranscriptomicsChIP-chip from DAOY cells stably expressing HA-MXD3 with anti-HA
A subset of medulloblastomas, the most common brain tumor in children, is hypothesized to originate from granule neuron precursors (GNPs) in which the sonic hedgehog (SHH) pathway is over-activated. MXD3, a basic helix-look-helix zipper transcription factor of the MAD family, has been reported to be...
ORGANISM(S): Homo sapiens 
2012-07-12 | E-GEOD-34050 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human glucose-dependent insulinotropic peptide (GIP)- and adrenocorticotropin-dependent adrenal hyperplasias reveals novel targets for the study of GIP-dependent Cushings syndrome.
The mechanisms responsible for the ectopic adrenal expression of glucose-dependent insulinotropic peptide (GIP) receptor (GIPR) in GIP-dependent Cushing's syndrome (CS) are unknown. Chronic adrenal stimulation by ACTH in Cushing's disease or GIP in GIP-dependent ACTH-independent macronodular adrenal...
ORGANISM(S): Homo sapiens 
2007-10-02 | E-GEOD-4060 | biostudies-arrayexpress
ProteomicsMudPIT analyses of whole cell extracts from Y1 murine adrenocortical carcinoma cell line stimulated with serum or FGF2
Fibroblast growth factor 2 (FGF2) is well known as a promoter of cell proliferation, however, in some cellular contexts, it can induce cell cycle arrest or cell death. In Y1 murine adrenocortical carcinoma cell line, FGF2 induces G0/G1 transition but delays S-phase progression and permanently block ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2017-10-23 | MSV000081638 | MassIVE
ProteomicsInteractome of chromatin-associated RNA Polymerase II from U2OS cells
To determine the interactome of RNA Polymerase II (RNAPII), HA-tagged RPB3 was stably expressed in U2OS cells. The cells were harvested followed by the native stepwise isolation of chromatin-associated RNAPII complexes. HA-RPB3 was immunoprecipitated and interacting proteins analyzed by quantitative...
ORGANISM(S): Homo sapiens (Human) 
2024-12-20 | PXD054701 | Pride
Interactome U2os Rnapii 
TranscriptomicsChromatin Immunoprecipitation microarray data from antiHA IP in stable LNCaP cells expressing either YFP or HA-SOX4/YFP
SOX4 is a critical developmental transcription factor in vertebrates and is required for precise differentiation and proliferation in multiple tissues. In addition, SOX4 is overexpressed in many human malignancies, but the precise role of SOX4 in cancer progression is not well understood. He...
ORGANISM(S): Homo sapiens 
2008-11-09 | E-GEOD-11874 | biostudies-arrayexpress
ProteomicsPhosphatidic acid features double membrane vesicle formation during Hepatitis C and SARS-CoV-2 infection
Double membrane vesicles (DMVs) are used as replication organelles by pathogenic RNA viruses such as hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Viral DMVs are morphologically analogous to DMVs formed during autophagy, and although the proteins required...
ORGANISM(S): Homo sapiens (Human) 
2022-01-24 | PXD029692 | Pride
Dmvs Lipid phosphatidic acid Sars-cov-2 Hepatitis c 
UnknownStructural Elucidation of Glycosaminoglycans in the Tissue of Flounder and Isolation of Chondroitin Sulfate C.
Not available
S-EPMC11123320 | biostudies-literature
UnknownHyaluronidases Have Strong Hydrolytic Activity toward Chondroitin 4-Sulfate Comparable to that for Hyaluronan.
Not available
S-EPMC4030862 | biostudies-literature
ProteomicsMechanical loading but not insertion into an enthesis is required for initiaion of myotendinous junction development
Data files included in this submission are from 4 separate experiments to show that myotendinous junction formation and muscle maturation is dependent on muscle contraction. For Tbx3 E14.5 and E18.5 CS and IN samples: forelimbs (n=3 each genotype and age) were fractionated into C, N, M, CS, and IN f...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-05-26 | MSV000089551 | MassIVE
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