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TranscriptomicsExpression data for human retinal pigment epithelium (RPE)/choroid - early age-related macular degeneration (AMD) and control samples
Purpose: Age-related degeneration (AMD) is a major cause of blindness in developed countries. The molecular pathogenesis of early events in AMD is poorly understood. We investigated differential gene expression in samples of human retinal pigment epithelium (RPE)/choroid from early AMD and control m...
ORGANISM(S): Homo sapiens 
2013-12-23 | E-GEOD-50195 | biostudies-arrayexpress
TranscriptomicsGenome wide expression responses of Fusarium oxysporum wt and M-NM-^ThapX mutant to iron depleted and iron replete conditions.
Soilborne fungal pathogens cause devastating yield losses, are highly persistent and difficult to control. To culminate infection, these organisms must cope with limited availability of iron. Here we show that the bZIP protein HapX functions as a key regulator of iron homeostasis and virulence in th...
ORGANISM(S): Fusarium oxysporum 
2012-07-13 | E-GEOD-39325 | biostudies-arrayexpress
TranscriptomicsComparing gene expression in stem/progenitor cells from patients with CML in chronic, accelerated and blastic phase with normal volunteers
A comparison of global gene expression between rigorously defined stem and progenitor cells from patients with chronic myeloid leukaemia (CML) in chronic (CP), accelerated (AP) and blastic (BC) phase and similar populations isolated from normal volunteers. Cryopreserved CD34+ enriched cell populatio...
ORGANISM(S): Homo sapiens 
2013-09-06 | E-GEOD-47927 | biostudies-arrayexpress
ProteomicsGlobal Protein Abundance and Phosphorylation Analyses of Influenza A Virus (IAV)-Infected Human Cells
Influenza A Virus (IAV) is a recurring respiratory virus with antiviral therapies of limited use. Understanding host proteins essential for IAV infection can identify targets for alternative host-directed therapies (HDTs). Using affinity purification-mass spectrometry and global phosphoproteomic and...
ORGANISM(S): Homo sapiens (Human) 
2023-07-25 | PXD035900 | Pride
Human H5n1 H1n1 Protein abundance Phosphorylation Nhbe H3n2 Thp-1 Infection Influenza a virus 
TranscriptomicsHER2 expression identifies dynamic functional states within circulating breast cancer cells
Circulating tumour cells in women with advanced oestrogen-receptor (ER)-positive/human epidermal growth factor receptor 2 (HER2)-negative breast cancer acquire a HER2-positive subpopulation after multiple courses of therapy. In contrast to HER2-amplified primary breast cancer, which is highly sensit...
ORGANISM(S): Homo sapiens 
2016-08-25 | E-GEOD-75367 | biostudies-arrayexpress
UnknownProteomic and genetic analyses of influenza A viruses identify pan-viral host targets.
Not available
S-EPMC10533562 | biostudies-literature
UnknownResults of the two incidence screenings in the National Lung Screening Trial.
Not available
S-EPMC4307922 | biostudies-literature
UnknownMapping the genetic landscape across 14 psychiatric disorders.
Not available
S-EPMC12779569 | biostudies-literature
UnknownPolygenic and developmental profiles of autism differ by age at diagnosis.
Not available
S-EPMC12571882 | biostudies-literature
UnknownPitavastatin to Prevent Cardiovascular Disease in HIV Infection.
Not available
S-EPMC10564556 | biostudies-literature
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