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ProteomicsShotgun proteomics of Roseburia grown on human milk oligosaccharides and of Roseburia grown on mucin in co-culture with Akkermansia muciniphilia.
The main objective of the present proteomic study is to identify the metabolic response, in particular theglycan uptake and degradation machinery, conferring members of Roseburia growth on HMOs and/or onrelated O-glycans. Accordingly, the proteomes of R. hominis and R. inulinivorans bothgrown on hum...
ORGANISM(S): Roseburia inulinivorans DSM 16841 Akkermansia muciniphila ATCC BAA-835 Roseburia hominis A2-183 
2020-07-06 | PXD015045 | Pride
Lc-msms Metaproteomics Roseburia Proteomics Hmos Mucin Akkermansia muciniphilia O-glycans 
ProteomicsThe Human Gut Firmicute Roseburia intestinalis is a Primary Degrader of Dietary β-Mannans
β-Mannans are plant cell wall polysaccharides that are commonly found in human diets. However, a mechanistic understanding into the key populations that degrade this glycan is absent, especially for the dominant Firmicutes phylum. Here, we show that the prominent butyrate-producing Firmicute Rosebur...
ORGANISM(S): Roseburia intestinalis L1-82 
2019-02-21 | PXD012448 | Pride
Roseburia intestinalis Q-exactive 
UnknownThe human gut Firmicute Roseburia intestinalis is a primary degrader of dietary β-mannans.
Not available
S-EPMC6385246 | biostudies-literature
UnknownMetabotropic glutamate receptor-1 regulates inflammation in triple negative breast cancer.
Not available
S-EPMC6207734 | biostudies-literature
Unknowngem-Difluorobisarylic derivatives: design, synthesis and anti-inflammatory effect.
Not available
S-EPMC6824041 | biostudies-literature
UnknownThe Quebec Cannabis Registry: Investigating the Safety and Effectiveness of Medical Cannabis.
Not available
S-EPMC10714117 | biostudies-literature
UnknownThe relationship between perceived social support and quality of life among hospitalized patients with schizophrenia.
Not available
S-EPMC12528428 | biostudies-literature
UnknownExtracorporeal Photopheresis for Bronchiolitis Obliterans Syndrome After Lung Transplantation.
Not available
S-EPMC7228625 | biostudies-literature
ProteomicsLabel free proteomic experiment using control and VARS-depleted RES M395 melanoma cultures
In this study, we combined quantitative proteomics and systematic codon usage analysis of translated mRNA, polysome and ribosome sequencing to uncover VARS translational targets.
ORGANISM(S): Homo sapiens (Human) 
2024-08-09 | PXD044910 | Pride
Lc-ms/ms Melanoma Vars depletion Human cells 
ProteomicsLabel free proteomic experiment using M395 sensitive and resistance melanoma cultures to targeted therapy
In this study, we combined tRNA sequencing, quantitative proteomics and systematic codon usage analysis of translated mRNA to uncover new mechanisms underlying translation reprogramming and therapy resistance in melanoma.
ORGANISM(S): Homo sapiens (Human) 
2024-08-09 | PXD044863 | Pride
Lc-ms/ms Melanoma Resistance Human cells Targeted therapy 
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