Sort   by:  
 Page size 
ProteomicsMolecular architecture of the augmin complex
Haus DSSO CX-MS analysis to validate Cyro-EM analysis of Haus multimer
ORGANISM(S): Homo sapiens (Human) 
2022-06-29 | PXD031411 | Pride
Augmin complex Haus Cx-ms 
ProteomicsRe-examining the role of Cdc14 phosphatase in mitotic exit
Given that Cdc14 enzymes are so highly conserved, we questioned whether budding yeast Cdc14 could really have such a different influence on Cdk site dephosphorylation. We used quantitative phosphoproteomics to directly measure the in vivo specificity of budding yeast Cdc14 and found that it very sel...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2017-07-13 | PXD005237 | Pride
Protein phosphatase Mitosis Cdc14 Cdk Mitotic exit Phosphoproteomics Cyclin-dependent kinase 
TranscriptomicsHUDEP1/HUDEP2 OE COUPTFII CUT&RUN
The experiment aim to show where COUPTFII is binding in Human cells as HUDEP21/2. The cells do not naturally express COUPTFII so we overexpressed it. We do then a comparison between the cells in which is not expressed and the on in which it is (and we compare the binding profile in HIDEP1 and HUDEP2...
ORGANISM(S): Homo sapiens 
2025-12-30 | E-MTAB-14720 | biostudies-arrayexpress
ProteomicsIdentification of novel kinases of Tau using fluorescence complementation mass spectrometry (FCMS)
Hyperphosphorylation of the microtubule-associated protein Tau is a major hallmark of Alzheimer’s disease (AD) and other tauopathies. Understanding the protein kinases that phosphorylate Tau is critical for the development of new drugs that target Tau phosphorylation. At present, the repertoire of t...
ORGANISM(S): Homo Sapiens (human) 
2022-11-10 | PXD036956 | JPOST Repository
TranscriptomicsCUT&RUN HUDEP1 OE SOX6-Flag
SOX6 CUT&RUN on HUDEP1 over expressing SOX6-Flag. The experiment is done using and anti Flag Ab to assist the genome wide binding profile of SOX6 in HUDEP1 (Human Umbilical cord blood-Derived Erythroid Progenitor-1).
ORGANISM(S): Homo sapiens 
2023-04-07 | E-MTAB-12800 | biostudies-arrayexpress
TranscriptomicsCUT&RUN LoV-U of beta-catenin, TCF/LEF transcription factors and histone modifications in HEK293T and mouse embryonic hindlimb tissue at 11.5 days post coitum
In our attempts to profile different regulators of the WNT/b-catenin transcriptional complex, CUT&RUN failed to produce consistent binding patterns of the non-DNA-binding b-catenin. We developed a modified CUT&RUN protocol, which we refer to as LoV-U (Low Volume and Urea), that enables the generatio...
ORGANISM(S): Mus musculus 
2022-07-16 | E-MTAB-11951 | biostudies-arrayexpress
TranscriptomicsCUT&RUN experiment at four time points in HEK293T and hESC cells, assessing the time-resolved response of β-catenin genomic occupancy upon Wnt signaling activation
Wnt/β-catenin signaling is a highly organized biochemical cascade that triggers a gene expression program in the signal-receiving cell. The Wnt/β-catenin-driven transcriptional response is involved in virtually all cellular processes during development, homeostasis, and its deregulation causes human...
ORGANISM(S): Homo sapiens 
2022-09-30 | E-MTAB-12077 | biostudies-arrayexpress
UnknownAdmixture and breed traceability in European indigenous pig breeds and wild boar using genome-wide SNP data.
Not available
S-EPMC9072372 | biostudies-literature
MetabolomicsSimultaneously discovering the fate and biochemical effects of pharmaceuticals through untargeted metabolomics
Untargeted metabolomics is an established approach in toxicology for characterising endogenous metabolic responses to xenobiotic exposure. Detecting the xenobiotic and its biotransformation products as part of the metabolomics analysis provides an opportunity to simultaneously gain deep insights int...
2023-07-03 | MTBLS2746 | MetaboLights
UnknownPrimary Results From the Understanding Outcomes With the S-ICD in Primary Prevention Patients With Low Ejection Fraction (UNTOUCHED) Trial.
Not available
S-EPMC7752215 | biostudies-literature
Sort   by:  
 Page size