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TranscriptomicsRetinoic Acid Enhances Foxp3 Induction Indirectly by Relieving Inhibition from CD4(+)CD44(hi) Cells.
CD4(+)Foxp3(+) regulatory T (Treg) cells originate primarily from thymic differentiation, but conversion of mature T lymphocytes to Foxp3 positivity can be elicited by several means, including in vitro activation in the presence of TGF-beta. Retinoic acid (RA) increases TGF-beta-induced expression o...
ORGANISM(S): Mus musculus 
2008-11-16 | E-GEOD-13306 | biostudies-arrayexpress
ProteomicsPhospho-proteomic characterization of human hepatocellular carcinoma (HCC) tumor biopsies
We analyzed the phospho-proteome of tumor and matched non-tumor biopsies from 51 treatment-naive Hepatocellular carcinoma (HCC) patients by label-free DDA. Thereby we aim to find subgroups of patients characterized by specific pathway activation. Furthermore, we aim to find novel factors involved in...
ORGANISM(S): Homo sapiens (Human) 
2022-03-14 | PXD025836 | Pride
Human Qexactive hf Phospho-proteomics Hepatocellular carcinoma (hcc) Biopsies 
UnknownMovement representations in motor, somatosensory, and posterior parietal cortex of the greater galago.
Not available
S-EPMC12368956 | biostudies-literature
MetabolomicsX-ray Irradiation Suppresses Keloid Growth by Inducing G2/M Arrest via the Phytosphingosine-KIF20A Axis
Keloid radiotherapy is clinically effective but has an incomplete underlying molecular mechanism and limited accessibility; we used X-ray exposure to identify effector pathways replicating its antifibrotic benefits without further radiation. After collecting patient keloid samples, primary human kel...
2026-06-06 | MTBLS14461 | MetaboLights
ProteomicsIntegrative analysis of Paneth cell proteomic data from intestinal organoids reveals functional processes affected in Crohn’s disease due to autophagy impairment
Crohn’s disease (CD) is associated with multiple Paneth cell dysfunctions such as altered antimicrobial secretion that relies on autophagy - an essential process controlling the turnover of cellular components. Genome-wide association studies have linked CD to mutations in the ATG16l1 gene, encoding...
ORGANISM(S): Mus musculus (Mouse) 
2019-03-07 | PXD010940 | Pride
Quantitative proteomics  selective autophagy  crohn’s disease Paneth cells  atg16l1  intestinal organoids 
UnknownIntegrative analysis of fitness and metabolic effects of plasmids in Pseudomonas aeruginosa PAO1.
Not available
S-EPMC6246594 | biostudies-literature
UnknownRevealing the Intrinsic Peroxidase-Like Catalytic Mechanism of Heterogeneous Single-Atom Co-MoS2.
Not available
S-EPMC7770872 | biostudies-literature
UnknownTargeting physical activity interventions for adults: When should intervention occur?
Not available
S-EPMC5337155 | biostudies-literature
ProteomicsMacaque models for influenza A virus
Non-human primates are the animals closest to humans for use in influenza A virus challenge studies, in terms of their phylogenetic relatedness, physiology and immune systems. Previous studies have shown that cynomolgus macaques (Macaca fascicularis) are permissive for infection with H1N1pdm influen...
ORGANISM(S): Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) Unidentified Influenza A virus (H1N1) 
2016-06-20 | PXD003803 | Pride
Label free proteomics H1n1pdm influenza virus Intra-nasal challenge 
UnknownDatabase Resources of the National Genomics Data Center, China National Center for Bioinformation in 2024.
Not available
S-EPMC10767964 | biostudies-literature
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