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TranscriptomicsDevelopmental transitions of Coxiella burnetii grown in axenic media
Coxiella burnetii undergoes a biphasic developmental cycle within its host cell that generates morphologically and physiologically distinct large cell variants (LCV) and small cell variants (SCV). During the lag phase of the C. burnetii growth cycle, non-replicating SCV differentiate into replicati...
ORGANISM(S): Coxiella burnetii 
2013-12-02 | E-GEOD-51135 | biostudies-arrayexpress
TranscriptomicsmiRNA expression profile in leprosy skin biopsy specimens
Skin biopsy specimens of skin lesions were profiled for miRNA expression. In this study, we indentified miRNA species that were differentially expressed in the skin lesions of either the lepromatous or tuberculoid forms of leprosy. One miRNA species, hsa-mir-21, found in the lepromatous lesions was...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-33192 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of migratory vs sedentary brown trout (Salmo trutta) and wild vs hatchery Atlantic salmon (Salmo salar)
A total of 55 individuals were analysed: 15 migratory brown trout (Salmo trutta) individuals from the Redon river, 15 sedentary brown trout (S. trutta) individuals from the Redon river, 15 sedentary brown trout (S. trutta) individuals from the Chevenne river, and 10 Atlantic salmon (S. salar) indivi...
ORGANISM(S): Salmo salar 
2006-03-27 | E-MEXP-123 | biostudies-arrayexpress
UnknownShift in ecological strategy helps marginal populations of shepherd's purse (Capsella bursa-pastoris) to overcome a high genetic load.
Not available
S-EPMC7287375 | biostudies-literature
TranscriptomicsTranscriptional profiling of Coxiella burnetii reveals extensive cell wall remodeling in the small cell variant developmental form
A hallmark of Coxiella burnetii, the bacterial cause of human Q fever, is a biphasic developmental cycle that generates biologically, ultrastructurally, and compositionally distinct large cell variant (LCV) and small cell variant (SCV) forms. LCVs are replicating, exponential phase forms while SCVs ...
ORGANISM(S): Coxiella burnetii 
2016-02-10 | E-GEOD-74489 | biostudies-arrayexpress
ProteomicsInteraction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling
Ubiquitin ligases (E3s) embedded in the endoplasmic reticulum (ER) membrane regulate essential cellular activities including protein quality control, calcium flux, and sterol homeostasis. At least 25 different, transmembrane domain (TMD)-containing E3s are predicted to be ER-localised, but for most ...
ORGANISM(S): Homo sapiens (Human) 
2020-07-06 | PXD019559 | Pride
Sting Innate immune response Ubiquitin ligase Endoplasmic reticulum Rnf26 
UnknownMeta-analysis of genome-wide association studies identifies 1q22 as a susceptibility locus for intracerebral hemorrhage.
Not available
S-EPMC3980413 | biostudies-literature
Unknown17p12 Influences Hematoma Volume and Outcome in Spontaneous Intracerebral Hemorrhage.
Not available
S-EPMC6085089 | biostudies-literature
UnknownGenetic variants influencing elevated myeloperoxidase levels increase risk of stroke.
Not available
S-EPMC5841027 | biostudies-literature
UnknownGenetic variants in CETP increase risk of intracerebral hemorrhage.
Not available
S-EPMC5115931 | biostudies-literature
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