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Although immune mechanisms have been described for Peyer’s patch function, in discriminating food nutrients and commensal microflora from pathogenic challenge, an understanding of gene expression patterns associated with normal intestinal homeostasis is lacking. The effects of commensal bacterial co...
ORGANISM(S): Sus scrofa 
2004-11-05 | GSE1913 | GEO
Although immune mechanisms have been described for Peyer’s patch function, in discriminating food nutrients and commensal microflora from pathogenic challenge, an understanding of gene expression patterns associated with normal intestinal homeostasis is lacking. The effects of commensal bacterial co...
ORGANISM(S): Sus scrofa 
Two C57BL/6 mice colonies maintained in two rooms in the same specific pathogen free (SPF) facility were found to have different gut microbiota and a mucus phenotype specific for each colony. The thickness and growth of the colon mucus was similar in the two colonies, but one colony had mucus not pe...
ORGANISM(S): Mus musculus (Mouse) 
2015-02-09 | PXD001479 | Pride
jejunal Peyer’s patch (JPP) gene expression relative to jejunal mesenteric lymph node (j-MLN) gene expression.

INTRODUCTION: Myxomatous mitral valve disease (MMVD) is the most common cardiac condition in adult dogs. The disease progresses over several years and affected dogs may develop congestive heart failure (HF). Research has shown that myocardial metabolism is altered in cardiac dise...

2022-03-31 | MTBLS716 | MetaboLights
Haematopoietic stem and progenitor cells (HSPCs) in the foetus and adult possess distinct molecular landscapes that regulate cell fate and change their susceptibility to initiation and progression of haematopoietic malignancies. The proteomic programs that govern these differences remain elusive. In...
ORGANISM(S): Mus musculus (Mouse) 
2017-12-12 | PXD006876 | Pride
DNA methylation is an important epigenetic modification that is thought to contribute to the maintenance of genomic integrity in somatic cells, in part through the silencing of transposable elements (TEs). In this study we used CRISPR/Cas9 mediated gene editing to disrupt DNMT1, the key maintenance ...
ORGANISM(S): Homo sapiens (Human) 
2019-05-30 | PXD008648 | Pride
Human bone marrow stromal cells (BMSCs) are key elements of the hematopoietic environment and they play a central role in bone and bone marrow physiology. However, how key BMSC functions are regulated is largely unknown. We analyzed the role of the immediate early response transcription factor EGR1 ...
ORGANISM(S): Homo sapiens (Human) 
2019-06-27 | PXD011767 | Pride
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