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TranscriptomicsExpression profiling of MRC5 senescent fibroblasts
Microarrays analysis identifies WNT16in senescent fibroblasts. To identify genes expressed in replicative senescence, microarray experiments were conducted in which we compared the RNA expression profile of young MRC5 fibroblasts at population doubling 28 (PDL28) and replicative senescent MRC5 fibro...
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-15919 | biostudies-arrayexpress
TranscriptomicsHEPATIC GENE EXPRESSION PATTERNS IN JUVENILE TURBOTS (Scophthalmus maximus) AFTER EXPOSURE TO NO2 FUEL OIL AND TO STYRENE (PRAGMA, a pragmatic and integrated approach for the evaluation of environmental impact of oil and chemical spills at sea)
Accidental spills of chemical or oil tankers such as Levoli Sun or Prestige have recently impacted the European seas. The analysis of the genes regulated by exposure to spilled chemical substances could help elucidating adaptatory and compensatory pathways that may participate in pathogenesis in mar...
ORGANISM(S): Scophthalmus maximus 
2016-07-31 | E-GEOD-43355 | biostudies-arrayexpress
TranscriptomicsHEPATIC GENE EXPRESSION PATTERNS IN JUVENILE TURBOTS (Scophthalmus maximus) AFTER EXPOSURE TO NO2 FUEL OIL (PRAGMA, a pragmatic and integrated approach for the evaluation of environmental impact of oil and chemical spills at sea)
Accidental spills of chemical or oil tankers such as Levoli Sun or Prestige have recently impacted the European seas. The analysis of the genes regulated by exposure to spilled chemical substances could help elucidating adaptatory and compensatory pathways that may participate in pathogenesis in mar...
ORGANISM(S): Scophthalmus maximus 
2016-07-31 | E-GEOD-43361 | biostudies-arrayexpress
MetabolomicsThe effect of changing haylages of differing chemical composition on the equid metabonome
Rapid changes between feeds can cause dysbiosis and colic. The metabolic consequences of changing between haylages is currently unknown. Objectives Characterise urinary and faecal metabonomics in ponies transitioned between haylages varying in botanical composition and physiological age and to deter...
2026-09-29 | MTBLS15865 | MetaboLights
TranscriptomicsImpact of Velvet complex on transcriptome and penicillin G production in glucose-limited chemostat cultures of a beta-lactam high-producing Penicillium chrysogenum strain
The multi-component global regulator Velvet complex has been identified as a key regulator of secondary metabolite production in Aspergillus and Penicillium species. Previous work indicated a massive impact of PcvelA and PclaeA deletions, two key components of the Velvet complex, on penicillin produ...
ORGANISM(S): Penicillium chrysogenum 
2011-12-06 | E-GEOD-31633 | biostudies-arrayexpress
Transcriptomicsp53 In Inflamatory Stress Response
Activation of the p53 network plays a central role in the inflammatory stress response associated with ulcerative colitis, and may modulate cancer risk in patients afflicted with this chronic disease. The overall goal of these experiments is to study the gene expression profiles associated with four...
ORGANISM(S): Homo sapiens 
2005-11-30 | E-GEOD-3176 | biostudies-arrayexpress
TranscriptomicsGenome-wide replication analysis of a yeast eco1 mutant by deep sequencing.
Eco1 is the acetyltransferase that establishes sister-chromatid cohesion during DNA replication. Budding yeast with an eco1 mutation that genocopies Roberts syndrome displaysreduced ribosomal DNA (rDNA) transcription and a transcriptional signature of starvation. Weshow that deleting FOB1, a gene en...
ORGANISM(S): Saccharomyces cerevisiae 
2014-04-03 | E-GEOD-54742 | biostudies-arrayexpress
TranscriptomicsThe cohesin acetyltransferase Eco1 coordinates rDNA replication and transcription
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Saccharomyces cerevisiae 
2014-04-03 | E-GEOD-54743 | biostudies-arrayexpress
TranscriptomicsHigh-throughput gene expression profiling of Salmonella enterica serovar Paratyphi A in the blood of bacteremic patients in Bangladesh
In this work, we applied an RNA analysis method, Selective Capture of Transcribed Sequences (SCOTS), and cDNA hybridization-microarray technology to identify S. Paratyphi A transcripts expressed by bacteria in the blood of three patients in Bangladesh. In total, we detected 1798 S. Paratyphi A mRNA...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Paratyphi A 
2010-09-06 | E-GEOD-22958 | biostudies-arrayexpress
TranscriptomicsIn vivo expression of Salmonella enterica serotype Typhi genes in the blood of patients with typhoid fever in Bangladesh
We applied an RNA capture and amplification technique, Selective Capture of Transcribed Sequences (SCOTS), and microarray hybridization to identify S. Typhi transcripts expressed in the blood of five humans infected with S. Typhi in Bangladesh. In total, we detected the expression of mRNAs for 2046...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhi 
2011-07-12 | E-GEOD-30565 | biostudies-arrayexpress
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