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UnknownD-xylose metabolism in Hypocrea jecorina: loss of the xylitol dehydrogenase step can be partially compensated for by lad1-encoded L-arabinitol-4-dehydrogenase.
Not available
S-EPMC219359 | biostudies-literature
TranscriptomicsInvestigations of gene expression in fathead minnow (Pimephales promelas) brain tissue reveal toxicological impacts of RDX exposure
Production, usage and disposal of the munitions constituent (MC) cyclotrimethylenetrinitramine (RDX) has led to environmental releases on military facilities. The chemical attributes of RDX are conducive for leaching to surface water which may put aquatic organisms at risk of exposure. Because RDX...
ORGANISM(S): Pimephales promelas 
2010-07-30 | E-GEOD-21153 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of Neurospora crassa conidia undergoing a time-course: ?pp-1 vs WT
To study the consequences of transcription factor pp-1 deletion during vegetative cell fusion, we performed whole genome microarrays of WT and ?pp-1 conidia during their initial growth period (3h - 8h). The WT (FGSC2489) and ?pp1 strains were analyzed at five different timepoints. Cy3 and Cy5 dye sw...
ORGANISM(S): Neurospora crassa OR74A 
2013-08-09 | E-GEOD-49679 | biostudies-arrayexpress
TranscriptomicsOne Year RDX Exposure, Brain Tissue Investigation
We investigated ecotoxicological effects and toxicogenomic responses in fathead minnows (Pimephales promelas) exposed to an environmentally-relevant concentration (0.83 mg/L) of the munitions compound cyclotrimethylenetrinitramine (RDX) in one year and multi-generational assays. In the one year ass...
ORGANISM(S): Pimephales promelas 
2010-07-30 | E-GEOD-21101 | biostudies-arrayexpress
TranscriptomicsEffect of a naturally eQTN on the yeast transcriptome
We identified a mutation that is a frameshift mutation in a mononucleotide run of eight consecutive T's in the coding region of the gene SSY1, which encodes a key component of a plasma-membrane sensor of extracellular amino acids.We introduced it into the S288c background and examined the effect on ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-26 | E-GEOD-9875 | biostudies-arrayexpress
MetabolomicsUntargeted metabolomics links glutathione to bacterial cell cycle progression
Cell cycle progression requires the coordination of cell growth, chromosome replication, and division. Consequently, a functional cell cycle must be coupled with metabolism. However, direct measurements of metabolome dynamics remained scarce, in particular in bacteria. Here, we describe an untargete...
2020-10-15 | MTBLS1402 | MetaboLights
ProteomicsMechanism of disaggregation of Tau fibrils in vivo
The interactome of fibrillar aggregates of the Tau repeat domain fused to YFP (TauRD-Y) was analyzed in HEK293T cells using SILAC. TauRD-Y was immunoprecipitated with anti-GFP antibody from lysates of SILAC-labeled cells expressing TauRD-Y in soluble form (light labeled; L), from cells containing ag...
ORGANISM(S): Homo sapiens (Human) 
2022-12-09 | PXD023400 | Pride
Amyloid fibrils  aaa+ chaperones  vcp/p97  disaggregation  prion-like aggregate spreading 
ProteomicsLFQ proteomics analysis of M. smegmatis treated with CymA and ecumicin (Part 1).
To assess the impact of the bactericidal compounds CymA and ecumicin on the mycobacterial proteome and to monitor proteome remodeling by the AAA+ ClpC1 protease machinery, we performed a LFQ proteomics analysis treating the cells at sub-bactericidal compound concentration. We identified new players ...
ORGANISM(S): Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
2023-06-07 | PXD037232 | Pride
Tuberculosis Tpd Protein degradation 
Unknown"Purplish Blue" or "Greenish Grey"? Indigo Qualities and Extraction Yields from Six Species.
Not available
S-EPMC11013892 | biostudies-literature
UnknownUsefulness of a Multiparent Advanced Generation Intercross Population With a Greatly Reduced Mating Design for Genetic Studies in Winter Wheat.
Not available
S-EPMC6291512 | biostudies-literature
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