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Nuclear clearance of TDP-43 into cytoplasmic aggregates is a key driver of neurodegeneration in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD), but the mechanisms are unclear. Here, we show that TDP-43 knockdown specifically reduces number and motility of RAB11-posi...
ORGANISM(S): Mus musculus (Mouse) 
2016-09-29 | PXD004744 | Pride
Mitochondria vary in morphology and function in different tissues, however little is known about their molecular diversity among cell types. To investigate mitochondrial diversity in vivo, we developed an efficient protocol to isolate cell type-specific mitochondria based on a new MitoTag mouse. We ...
ORGANISM(S): Mus musculus (Mouse) 
2019-09-03 | PXD010772 | Pride
Mitochondria vary in morphology and function in different tissues, however little is known about their molecular diversity among cell types. To investigate mitochondrial diversity in vivo, we developed an efficient protocol to isolate cell type-specific mitochondria based on a new MitoTag mouse. We ...
ORGANISM(S): Mus musculus (Mouse) 
2019-09-03 | PXD010781 | Pride
Mitochondria vary in morphology and function in different tissues, however little is known about their molecular diversity among cell types. To investigate mitochondrial diversity in vivo, we developed an efficient protocol to isolate cell type-specific mitochondria based on a new MitoTag mouse. We ...
ORGANISM(S): Mus musculus (Mouse) 
2019-09-03 | PXD010774 | Pride
A whole cerebellum proteome analysis was performed to compare the data to cell specific mitochondria proteomics in the same brain region.
ORGANISM(S): Mus musculus (Mouse) 
2019-09-03 | PXD013380 | Pride
Primary renal cell carcinoma (RCC) by Affymetrix GeneChip miRNA 4.0
GeneChip HTA 2.0 data of primary renal cell carcinoma (RCC) and RCC metastases related to Guergen et al, Front Oncol 12:2022 889789. Microarrays were normalized individually using the SCAN method from the R package SCAN.UPC (version 2.34.0). Probe sets were summarized on the Entrez GeneID level usin...
Primary renal cell carcinoma (RCC) and RCC metastases by Affymetrix GeneChip HTA 2.0
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