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The four members of the epidermal growth factor receptor (EGFR/ERBB) family form homo- and heterodimers which mediate ligand-specific regulation of many key cellular processes in normal and cancer tissues. While signaling through the EGFR has been extensively studied on the molecular level, signal t...
ORGANISM(S): Mus musculus (Mouse) 
2016-01-15 | PXD002665 | Pride
ERBB4 is a member of the epidermal growth factor receptor (EGFR)/ERBB subfamily of receptor tyrosine kinases that regulates cellular processes including proliferation, migration and survival. ERBB4 signaling is involved in embryogenesis and homeostasis of adult tissues, but also in human pathologies...
ORGANISM(S): Homo sapiens (Human) 
2020-06-24 | PXD019430 | Pride
Interactome of ErbB4 JM-a and JM-b in MDA-MB-468 cells.
ORGANISM(S): Homo sapiens (Human) 
2023-02-20 | PXD040166 | Pride
Convergent and divergent effects of two FL ERBB4 isoforms on gene expression in normal-like MCF10A mammary epithelial cells lacking endogeneous ERBB4 expression. Control vector (VEC) and ERBB4 expression MCF10A cells(CYT1 or CYT2) were serum starved for 48 hours and incubated with or without ERBB4 l...
ORGANISM(S): Homo sapiens 
Convergent and divergent effects of two ICD ERBB4 isoforms on gene expression in normal-like MCF10A mammary epithelial cells lacking endogeneous ERBB4 expression. Control vector (VEC) and ERBB4 expression MCF10A cells (ICD CYT1 or CYT2) maintained in regular medium containing 10% serum, were collect...
ORGANISM(S): Homo sapiens 
Excitatory Neuronal ErbB4 Drives Early Pathophysiology of Alzheimer's Disease
Transcriptional profiling of ErbB4-/- mouse liver tissues comparing controls. Two-condition experiment, ErbB4-/- vs. control mouse liver tissues. Biological replicates: 3 controls, 3 ErbB4-/- mice.
ORGANISM(S): Mus musculus 
Small-Molecule-Induced ERBB4 Activation to Treat Heart Failure
Small-Molecule-Induced ERBB4 Activation to Treat Heart Failure
RNA-Seq of M1 activated ErbB4-null and WT bone-marrow macrophages.
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