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TranscriptomicsIdentification of differentially expressed miRNAs in HCC cell lines compared with normal livers
To explore functionally crucial tumor-suppressive (TS)-miRNAs in hepatocellular carcinoma (HCC), we performed integrative function- and expression-based screenings of TS-miRNAs in six HCC cell lines. The screenings identified seven miRNAs, which showed growth-suppressive activities through the over...
ORGANISM(S): Homo sapiens 
2013-05-31 | E-GEOD-41077 | biostudies-arrayexpress
ProteomicsIn-depth proteome profiling of small extracellular vesicles isolated from cancer cell lines and patient serum
Extracellular Vesicle (EV) secretion has been observed from most types of normal and tumor cells. These EVs contain a variety of distinctive cargo where tumor-derived serum proteins in EVs secreted into the bloodstream can be used to provide a minimally invasive method for clinical monitoring. We ha...
ORGANISM(S): Homo Sapiens (human) 
2024-09-08 | PXD045198 | JPOST Repository
TranscriptomicsExpression data comparing PLC8024 CD133+ and CD133- HCC cells
To identify candidate genes involved in enhanced tumorigenicity of CD133+ liver tumor-initiating cells Affymetrix Human Genome U133 Plus GeneChip 2.0 HCC cell line PLC8024 was sorted into CD133+ and CD133- populations by flow cytometry
ORGANISM(S): Homo sapiens 
2012-04-04 | E-GEOD-23451 | biostudies-arrayexpress
TranscriptomicsExpression data comparing Huh7 CD133+ and CD133- HCC cells
To identify candidate genes involved in enhanced tumorigenicity of CD133+ liver tumor-initiating cells Affymetrix Human Genome U133 Plus GeneChip 2.0 HCC cell line Huh7 was sorted into CD133+ and CD133- populations by flow cytometry
ORGANISM(S): Homo sapiens 
2012-04-04 | E-GEOD-23450 | biostudies-arrayexpress
TranscriptomicsComparison of two hepatocellular cancer cell lines with distinct properties regarding epithelial-mesenchymal transition
The epithelial to mesenchymal transition (EMT) of malignant hepatocytes is a crucial event in hepatocellular carcinoma (HCC) progression and recurrence. We aimed to establish a human model of EMT to examine drug efficacy and specificity in HCC progression. Human HCC cell populations were characteriz...
ORGANISM(S): Homo sapiens 
2011-11-21 | E-GEOD-26391 | biostudies-arrayexpress
GenomicsHCC-derived SNU cell lines as model systems to study HBV life cycle
HCC-derived SNU cell lines as model systems to study HBV life cycle
PRJNA1268435 | ENA
ProteomicsTumour-associated antigenic peptides are present in the HLA class I ligandome of cancer cell line derived extracellular vesicles.
The recent success of monoclonal antibody checkpoint inhibitor therapies that enhance the ability of CD8+ T cells to detect cancer-related antigenic peptides has refocused the need to fully understand the repertoire of peptides being presented to the immune system. Whilst the peptide ligandome prese...
ORGANISM(S): Homo sapiens (Human) 
2022-04-01 | PXD025345 | Pride
Cancer Extracellular vesicles T-cell epitopes Taa Hla class i ligandome Evs Tumour. Tumour-associated antigens 
UnknownGenerating Patient-Derived HCC Cell Lines Suitable for Predictive In Vitro and In Vivo Drug Screening by Orthotopic Transplantation.
Not available
S-EPMC10778205 | biostudies-literature
GenomicsInvestigation of mechanism using highly intrahepatic metastatic cell lines of HCC
Investigation of mechanism using highly intrahepatic metastatic cell lines of HCC
PRJNA635025 | ENA
TranscriptomicsExpression profiling of HCC
61 human HCCs were analyzed for genome-wide gene expression. Samples were collected at two sites in Germany, Heidelberg (HD) and Hannover (N). The Heidelberg Collection include 40 independent HCC: 19 liver resections and 17 explant liver specimen (4 not determined); median age at surgery was 57 year...
ORGANISM(S): Homo sapiens 
2013-09-05 | E-GEOD-50579 | biostudies-arrayexpress
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