Sort   by:  
 Page size 
UnknownNeuroprotection by histone deacetylase-related protein.
Not available
S-EPMC1447420 | biostudies-literature
UnknownIdentification of a transcriptional repressor related to the noncatalytic domain of histone deacetylases 4 and 5.
Not available
S-EPMC15519 | biostudies-literature
UnknownHistone deacetylase-1 (HDAC1) is a molecular switch between neuronal survival and death.
Not available
S-EPMC3471765 | biostudies-literature
TranscriptomicsExpression data from P14 TCR cytotoxic T cells overexpressing HDAC7 phosphorylation deficient mutant
The present study reports an unbiased analysis of the cytotoxic T cell serine-threonine phosphoproteome using high resolution mass spectrometry. Approximately 2,000 phosphorylations were identified in CTLs of which approximately 450 were controlled by TCR signaling. A significantly overrepresented g...
ORGANISM(S): Mus musculus 
2011-03-13 | E-GEOD-27092 | biostudies-arrayexpress
TranscriptomicsVascular histone deacetylation by pharmacological HDAC inhibition [SAHA, RNA-seq]
HDAC inhibitors are thought to regulate gene expression by post-translational modification of histone as well as non-histone proteins. Often studied at single loci, increased histone acetylation is the paradigmatic mechanism of action, however, little is known of the extent of genome-wide changes of...
ORGANISM(S): Homo sapiens 
2014-02-23 | E-GEOD-54912 | biostudies-arrayexpress
TranscriptomicsA Dach2-Hdac9-Myog-Gdf5 signaling system regulates regeneration of neuromuscular synapses
Muscle denervation due to injury, disease or aging results in impaired motor function. Restoring neuromuscular communication requires axonal regrowth and regeneration of neuromuscular synapses. Muscle activity inhibits neuromuscular synapse regeneration. The mechanism by which muscle activity regu...
ORGANISM(S): Mus musculus 
2015-10-29 | E-GEOD-58669 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of histone deacetylase inhibition in epithelioid sarcoma
Epithelioid Sarcoma (ES) is a rare neoplasm uniquely comprised of cells exhibiting both mesenchymal and epithelial features. Having propensity for local and distant recurrence, it can pose a diagnostic dilemma secondary to pathologic complexity. Patients have dismal prognosis due to lack of effectiv...
ORGANISM(S): Homo sapiens 
2015-11-03 | E-GEOD-66800 | biostudies-arrayexpress
TranscriptomicsVascular histone deacetylation by pharmacological HDAC inhibition [TSA, RNA-seq]
HDAC inhibitors are thought to regulate gene expression by post-translational modification of histone as well as non-histone proteins. Often studied at single loci, increased histone acetylation is the paradigmatic mechanism of action, however, little is known of the extent of genome-wide changes of...
ORGANISM(S): Homo sapiens 
2014-02-23 | E-GEOD-37376 | biostudies-arrayexpress
GenomicsHDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibroadipogenic progenitors in dystrophic muscles
Fibro-adipogenic progenitors (FAPs) are emerging cellular components of the skeletal muscle regenerative environment. The alternative functional phenotype of FAPs - either supportive of muscle regeneration or promoting fibro-adipogenic degeneration M-bM-^@M-^S is a key determinant in the pathogenesi...
ORGANISM(S): Mus musculus 
2014-04-02 | E-GEOD-52062 | biostudies-arrayexpress
ProteomicsBacteria initiates inflammaging leading to degenerative disc disease- evidence from host defense mechanism
Inflammaging is an established cause of degenerative disc disease (DDD), the possible triggers being genetic, mechanical, or infective. With rising evidence of subclinical infection and dysbiosis as initiators of degeneration, this study was undertaken to investigate the sequential molecular events ...
ORGANISM(S): Homo sapiens (Human) 
2025-01-07 | PXD023359 | Pride
Human Intervertebral disc Np Infection Hdrp 
Sort   by:  
 Page size