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MetabolomicsGeneration of a chromosome-scale genome assembly of the insect-repellent terpenoid-producing Lamiaceae species, Callicarpa americana

BACKGROUND: Plants exhibit wide chemical diversity due to the production of specialized metabolites that function as pollinator attractants, defensive compounds, and signaling molecules. Lamiaceae (mints) are known for their chemodiversity and have been cultivated for use as culi...

2020-12-04 | MTBLS1983 | MetaboLights
UnknownSpecies-Specific Responses of Bloom-Forming Algae to the Ocean Warming and Acidification.
Not available
S-EPMC11396949 | biostudies-literature
ProteomicsThe METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates metabolism and development via translation (Identification of m1A mRNA methyltransferase in nucleus by TMT11-LC-MS/MS)
m1A has long been known to be important in tRNA and rRNA, but we recently mapped many m1A sites in mRNA as well. m1A is found on the 5’ ends of genes, usually around the first splice site, but we have yet to understand how it effects transcript fate. Identifying the methyltransferase would be a ma...
ORGANISM(S): Homo sapiens (Human) 
2021-11-30 | PXD028832 | Pride
Mettl5 Mass spectrometry Proteomics M1a mrna methyltransferase Trmt112 
MetabolomicsMethionine Intervention Induces PD-L1 Expression to Enhance the Immune Checkpoint Therapy Response in MTAP-deleted Osteosarcoma
Osteosarcoma (OS), a malignant bone tumor with limited treatment options, exhibits low sensitivity to immune checkpoint therapy (ICT). Through genomics and transcriptomics analyses, we have identified a subgroup of OS with methylthioadenosine phosphorylase (MTAP) deletion, which contributes to ICT r...
2026-06-09 | MTBLS11985 | MetaboLights
UnknownPCDHGB7 inhibits the progression of triple-negative breast cancer by suppressing XRCC5/MYC-mediated ribosome biogenesis.
Not available
S-EPMC12405659 | biostudies-literature
GenomicsIgA Nephropathy GWAS (IGANGWAS)

We report a genome-wide association study of IgA nephropathy, a main cause of kidney failure. All subjects were of Chinese Han ancestry, of which 1,194 were cases and 902 controls. Genomic DNA samples extracted from whole blood were genotyped on the Illumina 610 Quad platform.

phs000431.v1.p1 | EGA
ProteomicsProteomic profiling of the kidney tissue scaffold from normal and fibrotic kidneys
The proteomic profiling of the kidney tissue scaffold derived from normal and fibrotic kidneys was carried out by an unbiased LC-MS/MS approach.
ORGANISM(S): Mus <genus> 
2023-03-15 | PXD034281 |
ProteomicsProteomics reveals that immunoglobulin abnormalities and immune dysregulation in patients with post–COVID-19 condition
Vitamin D (VD) has a coordinated immune function. Decreased VD levels are closely related to the occurrence of post-COVID-19 Conditions (PCC), but the specific mechanism is still unclear. Methods: We collected 50 PCC patient serum samples and divided them into three groups by different VD levels: VD...
ORGANISM(S): Homo Sapiens 
2025-11-27 | PXD059686 |
UnknownIntra-arterial selective hypothermia for acute ischemic stroke neuroprotection: A multicenter pilot trial in China
Not available
S-EPMC12289068 | biostudies-literature
ProteomicsThe rice aspartyl-tRNA synthetase YLC3 regulates amino acid homeostasis and chloroplast development under low temperature
Aminoacyl tRNA synthetases are key enzymes in protein synthesis, attaching the proper amino acid to the corresponding tRNA to make protein. However, their roles in regulating plant growth and development still remain elusive. Here we reported a rice thermo-sensitive mutant yellow leaf chlorosis3 (yl...
ORGANISM(S): Oryza Sativa 
2022-02-08 | PXD031497 |
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