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ProteomicsER-phagy restrains inflammatory responses through receptor UBAC2
ER-phagy, a selective degradation of endoplasmic reticulum (ER) fragment, plays a critical role in maintaining the ER homeostasis. Dysregulation of ER-phagy is involved in the unfolded protein response (UPR), which serves as a vital clue to evoke inflammatory disease. However, the molecular mechanis...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD052418 | Pride
Er-phagy  ubac2  mark2  inflammatory responses  colitis 
ProteomicsER-phagy restrains inflammatory responses through receptor UBAC2
ER-phagy, a selective degradation of endoplasmic reticulum (ER) fragment, plays a critical role in maintaining the ER homeostasis. Dysregulation of ER-phagy is involved in the unfolded protein response (UPR), which serves as a vital clue to evoke inflammatory disease. However, the molecular mechanis...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD052877 | Pride
Er-phagy  ubac2  mark2  inflammatory responses  colitis 
UnknownExpression reduction in mammalian X chromosome evolution refutes Ohno's hypothesis of dosage compensation.
Not available
S-EPMC3406839 | biostudies-literature
UnknownClinical and Molecular Landscape of GLRA2 in X-Linked Early-Onset High Myopia.
Not available
S-EPMC12007679 | biostudies-literature
UnknownDeveloping a construction waste management performance calculator for highway construction.
Not available
S-EPMC11557856 | biostudies-literature
MetabolomicsThe Toxoplasma micropore mediates endocytosis for selective nutrient salvage from host cell compartments

Apicomplexan parasite growth and replication relies on nutrient acquisition from host cells, in which intracellular multiplication occurs, yet the mechanisms that underlie the nutrient salvage remain elusive. Numerous ultrastructural studies have documented a plasma membrane invagination with a d...

2023-04-19 | MTBLS7006 | MetaboLights
UnknownImproving the Thermostability of Thermomyces lanuginosus Lipase by Restricting the Flexibility of N-Terminus and C-Terminus Simultaneously via the 25-Loop Substitutions.
Not available
S-EPMC10706272 | biostudies-literature
ProteomicsHepatic AKAP1 Deficiency Exacerbates Diet-Induced MASLD by Enhancing GPAT1-mediated Lysophosphatidic Acid Synthesis
Metabolic dysfunction-associated steatotic liver disease (MASLD), closely associated with obesity, can progress to metabolic dysfunction-associated steatohepatitis when the liver undergoes overt inflammatory damage. A-kinase anchoring protein 1 (AKAP1) has been shown to control lipid accumulation in...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-26 | PXD062388 | Pride
Akap1  masld  lysophosphatidic acid  gpat1  triglyceride synthesis. 
UnknownSystems pharmacology-based optimization of Ma Xing Shi Gan components for the enhanced treatment of chick health issues caused by infectious bronchitis virus.
Not available
S-EPMC12367666 | biostudies-literature
UnknownFunctional variants in the promoter region of Chitinase 3-like 1 (CHI3L1) and susceptibility to schizophrenia.
Not available
S-EPMC1785314 | biostudies-literature
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