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MetabolomicsGlobal analysis of plasma lipidomics reveals altered lipid signatures in patients with osteonecrosis of the femoral head

AIMS: Although studies have made the connection between lipid metabolism disorder and osteonecrosis of the femoral head (ONFH), the characteristics of the circulating lipidome signature of ONFH have not yet been investigated yet and need to be explored.

METHODS:

2021-07-06 | MTBLS2262 | MetaboLights
ProteomicsQuantitative Rps2 BioID to monitor Asc1-dependent rearrangement at the head region of the 40S ribosome
In a previous study we applied a quantitative proximity-labeling technique called Biotin Identification (BioID, Roux et al., 2012) to analyze the microenvironment of the Gβ-like scaffold protein Asc1 (Opitz et al., 2017). The WD40-repeat protein Asc1 binds to the head region of the small 40S ribosom...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-11-07 | PXD015611 | Pride
Asc1 Bre5 Sro9 Bioid Def1 Stm1 Rps2 Silac Ribosome Rps3 Translation Ubp3 Saccharomyces cerevisiae Vps30 
UnknownOcular hypertension suppresses homeostatic gene expression in optic nerve head microglia of DBA/2 J mice.
Not available
S-EPMC7249412 | biostudies-literature
ProteomicsSplit-TurboID with Bre5 and Rps2 in Saccharomyces cerevisiae
The in vivo labeling technique Split-Biotin identification (Split-BioID, De Munter et al., 2017, Schopp et al., 2017, Cho et al., 2020) was used to capture the common microenvironment of Bre5 and the ribosomal protein Rps2 (uS5). Biotinylated proteins were enriched from cell lysates using affinity p...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-11-10 | PXD028879 | Pride
Split-turboid Rps2 Split-bioid Us5 Silac Saccharomyces cerevisiae Ribosome Bre5 
UnknownA Novel Hydroxamate-Based Compound WMJ-J-09 Causes Head and Neck Squamous Cell Carcinoma Cell Death via LKB1-AMPK-p38MAPK-p63-Survivin Cascade.
Not available
S-EPMC5837967 | biostudies-literature
TranscriptomicsGene expression characterization of HPV positive head and neck cancer to predict response to Chemoradiation
Background: Human papillomavirus has been shown to have a causal role in the development of head and neck squamous cell carcinoma and represents a distinct and well-defined pathology. While HPV-positive HNSCC is associated with a better response to treatment and prognosis, a subset of patients do no...
ORGANISM(S): Homo sapiens 
2014-12-19 | E-GEOD-40020 | biostudies-arrayexpress
ProteomicsMultisite proteome provides insights into the biology and prognostic markers for head and neck cancer
The poor prognosis of head and neck cancer (HNC) is largely associated with the presence of metastasis in the lymph nodes (LN). Herein, the proteome of 140 multisite samples from a 59-HNC patient cohort, including primary and matched LN tissues, saliva, and blood cells, reveals insights into the bio...
ORGANISM(S): Homo Sapiens 
2022-11-22 | PXD027984 | panorama
ProteomicsMultisite proteome provides insights into the biology and prognostic markers for head and neck cancer
The poor prognosis of head and neck cancer (HNC) is largely associated with the presence of metastasis in the lymph nodes (LN). Herein, the proteome of 140 multisite samples from a 59-HNC patient cohort, including primary and matched LN tissues, saliva, and blood cells, reveals insights into the bio...
ORGANISM(S): Homo Sapiens 
2022-11-22 | PXD036311 | panorama
TranscriptomicsAnalysis of the transcriptional responses in inflorescence buds of Jatropha curcas exposed to cytokinin treatment
Jatropha curcas L. is a potential biofuel plant. Application of exogenous cytokinin (6-benzyladenine, BA) on its inflorescence buds can significantly increase the number of female flowers, thereby improving seed yield. To investigate which genes and signal pathways are involved in the response to cy...
ORGANISM(S): Jatropha curcas 
2014-12-14 | E-GEOD-54366 | biostudies-arrayexpress
TranscriptomicsComparison of lymph node negative (N0) and lymph node metastasis (N+) head and neck squamous-cell carcinomas (HNSCC)
A classifier was build on 82 training samples to differentiate between lymph node negative (N0) and lymph node metastasis (N+) head and neck squamous-cell carcinomas (HNSCC). The 102 predictor genes that resulted from this classifier where then validated against a independent validation set.
ORGANISM(S): Homo sapiens 
2005-01-09 | E-UMCU-11 | biostudies-arrayexpress
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