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Metabolomics1H HR-MAS NMR based metabolomics of cancer cells responding to two different doses of the diruthenium trithiolato complex [(p-MeC6H4iPr)2Ru2(SC6H4-p-But)3]+ (DiRu-1)
The trithiolato bridged diruthenium complex DiRu-1 [(p-MeC6H4iPr)2Ru2(SC6H4-p-But)3]+ is highly cytotoxic against various cancer cell lines, but its exact mode of action remained unknown. The present 1H HR-MAS NMR based metabolomic study performed on the ovarian cancer cell lines A2780, its cisPt re...
2019-07-04 | MTBLS1014 | MetaboLights
MetabolomicsUrine metabolomic profiling in two siblings with biallelic pathogenic ATG7 variants with healthy control
Ultra-rare biallelic ATG7 variants were recently reported in five families presenting with neurodevelopmental disorders. Two adult female siblings (P1 and P2) from one family carried compound heterozygous loss-of-function variants (c.1975C>T [p.Arg659]; c.2080-2A>G, 39,40NM_006395.2), resulting in u...
2026-09-30 | MTBLS15856 | MetaboLights
TranscriptomicsTranscription profiling of Baseline gene expression in circulating peripheral blood mononuclear cells isolated from 18 apparently healthy volunteers (10 females and 8 males)
Baseline gene expression in circulating peripheral blood mononuclear cells isolated from 18 apparently healthy volunteers (10 females and 8 males). The volunteers fasted overnight for 10 hours prior to collection of blood samples (but they were allowed water). 5 blood samples were collected from eac...
ORGANISM(S): Homo sapiens 
2013-01-30 | E-TABM-7 | biostudies-arrayexpress
GenomicsMapping of 5-hydroxymethylcytosine by selective chemical labeling (SCL-seq) in human naive B cells and in vitro differentiated plasmablasts (P1 cells) [HTS]
We report the genome-wide mapping of 5hmC in naive B cells and in vitro differentiated plasmablasts (P1 cells). In addition, H3K4me1 and H3K27ac histne marks were mapped in in vitro differentiated plasmablasts from two healthy donors (BN358 and BN369) by ChIP-seq. Genomic DNA from human primary cell...
ORGANISM(S): Homo sapiens 
2015-10-30 | E-GEOD-72360 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human lymphocytes from healthy individuals given selenium supplements
The effects of selenium supplementation to healthy individuals using a microarray approach.
ORGANISM(S): Homo sapiens 
2007-12-10 | E-MEXP-1046 | biostudies-arrayexpress
ProteomicsLC-MSMS of RIBOPROTEOMES OF HEALTHY, POTATO VIRUS A- AND AGROBACTERIUM -INFECTED NICOTIANA BENTHAMIANA PLANTS
Nicotiana benthamiana is an important model plant for plant-microbe interaction studies. We compared the proteomes of ribosomes purified from healthy N. benthamiana plants and plants that were infected with two plant pathogens potato virus A (PVA genus Potyvirus) and A. tumefaciens bacteria. Ribosom...
ORGANISM(S): Rhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium radiobacter) Nicotiana benthamiana Potato virus A 
2018-12-05 | PXD011602 | Pride
Lc-msms Ribosome Agrobacterium tumefaciens Healthy plants Potato virus a Plant Nicotiana benthamiana 
TranscriptomicsTranscription profiling of human chondrogenic progenitor cells in P1 of 3 male and 3 female patients with late-stage osteoarthritis in comparison to healthy chondrocytes in P1
The regeneration of diseased hyaline cartilage remains a great challenge, mainly because degeneration activities after major injury or due to age-related processes overwhelm the self-renewal capacity of the tissue. We show that repair tissue from human articular cartilage of late stages of osteoarth...
ORGANISM(S): Homo sapiens 
2008-04-07 | E-GEOD-10575 | biostudies-arrayexpress
UnknownRandomized Phase I: Safety, Immunogenicity and Mucosal Antiviral Activity in Young Healthy Women Vaccinated with HIV-1 Gp41 P1 Peptide on Virosomes.
Not available
S-EPMC3577797 | biostudies-literature
GenomicsMapping of 5-hydroxymethylcytosine by selective chemical labeling (SCL-seq) in human naive B cells and in vitro differentiated plasmablasts (P1 cells) [HTS]
We report the genome-wide mapping of 5hmC in naive B cells and in vitro differentiated plasmablasts (P1 cells). In addition, H3K4me1 and H3K27ac histne marks were mapped in in vitro differentiated plasmablasts from two healthy donors (BN358 and BN369) by ChIP-seq.
ORGANISM(S): Homo sapiens 
2015-10-30 | GSE72360 | GEO
Unknown8-Methoxypsoralen is a competitive inhibitor of glutathione S-transferase P1-1.
Not available
S-EPMC4179718 | biostudies-literature
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