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MetabolomicsA multi-omics dataset of heat-shock response in the yeast RNA binding protein Mip6 (NMR assay)

Gene expression is a biological process regulated at different molecular levels, including chromatin accessibility, transcription, and RNA maturation and transport. In addition, these regulatory mechanisms have strong links with cellular metabolism. Here we present a multi-omics dataset that capt...

2020-02-14 | MTBLS1320 | MetaboLights
TranscriptomicsTransient Genotype-by-Environment Interactions in the Yeast Genomic Expression Response to Heat Shock
Microarray time courses followed the response of 5 yeast strains to heat shock. Expression variation due to genetic, environmental, and genotype-by-environment interactions were identified. Keywords: Timecourse and single timepoint expression studies of stress response in yeast The genomic express...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-18 | E-GEOD-15147 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of recombinant E. coli to heat-shock and dual heat-shock recombinant protein induction
Recombinant Escherichia coli cultures are used to manufacture numerous therapeutic proteins and industrial enzymes, where many of these processes use elevated temperatures to induce recombinant protein production. The heat-shock response in wild-type E. coli has been well studied. In this study, t...
ORGANISM(S): Escherichia coli 
2009-08-25 | E-GEOD-17507 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of Escherichia coli O157:H7 EDL933 during heat shock using microarrays
The transcriptome of Escherichia coli K-12 has been widely studied over a variety of conditions for the past decade while such studies involving E. coli O157:H7, its pathogenic cousin, are just now being conducted. To better understand the impact of heat shock on E. coli O157:H7, global transcript l...
ORGANISM(S): Escherichia coli 
2009-04-01 | E-GEOD-11463 | biostudies-arrayexpress
MetabolomicsModulation of liver metabolism and gut microbiota by Alhagi-honey alleviated heat stress-induced liver damage

Alhagi-honey (AH) is a well-established traditional ethnic medicine with advantageous effects against diarrhea and headaches. We aim to explore the preventive effect of AH on liver damage induced by heat stress (HS) and its underlying mechanism. HS models were established by thermostat, and mice ...

2024-09-23 | MTBLS10021 | MetaboLights
TranscriptomicsDissection of the heat-shock response in Mycobacterium tuberculosis using mutants and microarrays
Regulation of the expression of heat-shock proteins plays an important role in the pathogenesis of Mycobacterium tuberculosis. The heat-shock response of bacteria involves genome-wide changes in gene expression. A combination of targeted mutagenesis and whole-genome expression profiling was used to ...
ORGANISM(S): Mycobacterium tuberculosis 
2007-03-07 | E-BUGS-2 | biostudies-arrayexpress
TranscriptomicsGenomics of the individual heat shock response
The transcriptional response to heat shock is essential for cells to function effectively under stress. This is a highly heritable trait but the nature and extent of inter-individual variation in heat shock response are not well established. This dataset consists of the global transcription profiles...
ORGANISM(S): Homo sapiens 
2016-08-26 | E-MTAB-4953 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse cell culture treated with LPS to identify of inflammatory genes suppressed by heat shock
To clarify inflammatory genes whose expression is suppressed at high temperatures, we performed comprehensive analysis of gene expression by using a DNA microarray. Two independent primary cultures of mouse embryo fibroblasts (MEF1 and MEF2) were treated with LPS for 4 hours, or treated with LPS for...
ORGANISM(S): Mus musculus 
2010-01-19 | E-GEOD-16266 | biostudies-arrayexpress
MetabolomicsExploring the variations in intestinal microbial communities and metabolite profiles between heat-sensitive and heat-tolerant chickens through a comprehensive multi-omics approach

Heat stress (HS) compromises poultry health by disrupting intestinal integrity and microbiota homeostasis. This study compared heat stress-susceptible (HS-SUS) and heat stress-resistant (HS-RES) White Leghorn chickens under chronic cyclic HS (35±2°C, 8 h/day). HS-RES chickens demonstrated superio...

2025-09-12 | MTBLS12991 | MetaboLights
TranscriptomicsThe heat shock response of killifish (Fundulus heteroclitus): candidate gene and heterologous microarray approaches.
Subspecies of the Atlantic killifish, Fundulus heteroclitus, differ in their maximum thermal tolerance. To determine whether there is a link between the heat shock response (HSR) and maximum thermal tolerance, we exposed 20ºC acclimated killifish from these subspecies to a 2hr heat shock at 34ºC ...
ORGANISM(S): Fundulus heteroclitus 
2010-06-20 | E-GEOD-18792 | biostudies-arrayexpress
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