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UnknownA new method for the synthesis of H(4)-BINOL.
Not available
S-EPMC2587137 | biostudies-literature
TranscriptomicsTranscription profiling of hepatic response to anti-diabetic drug and dietary lifestyle interventions in LDLR-/- mice
Lean male mice were fed a high fat diet (HFD, lard 24% w/w) for 16 weeks. At 9 weeks, when all hallmarks of prediabetes were established, groups of mice were treated with drug (metformin, glibenclamide, sitagliptin, rosiglitazone, pioglitazone, fenofibrate, T0901317, atorvastatin, salicylate or rofe...
ORGANISM(S): Mus musculus 
2013-04-18 | E-MTAB-1063 | biostudies-arrayexpress
TranscriptomicsHuman umbilical vein endothelial cells (HUVECs) treated with fenofibrate
This SuperSeries is composed of the following subset Series: GSE15482: The effect of PPARa siRNA on endothelial cells treated with fenofibrate GSE15483: The effect of fenofibrate on endothelial cells Refer to individual Series
ORGANISM(S): Homo sapiens 
2009-08-24 | E-GEOD-15494 | biostudies-arrayexpress
TranscriptomicsThe effect of fenofibrate on endothelial cells
Fenofibrate is a synthetic ligand for the nuclear receptor peroxisome proliferator-activated receptor (PPAR) alpha, but there are reports that fenofibrate affects endothelial cells in PPARa-independent manner. In order to identify PPARa-dependently and PPARa-independently regulated transcripts we ge...
ORGANISM(S): Homo sapiens 
2010-05-06 | E-GEOD-15483 | biostudies-arrayexpress
TranscriptomicsThe effect of PPARa siRNA on endothelial cells treated with fenofibrate
Fenofibrate is a synthetic ligand for the nuclear receptor peroxisome proliferator-activated receptor (PPAR) alpha, but there are reports that fenofibrate affects endothelial cells in PPARa-independent manner. In order to identify PPARa-dependently and PPARa-independently regulated transcripts we ge...
ORGANISM(S): Homo sapiens 
2009-08-24 | E-GEOD-15482 | biostudies-arrayexpress
TranscriptomicsLinalool, an aromatic terpenoid, rewires transcriptome profile of lipid-loaded HepG2 cells
The microarray results showed that linalool sitimulation of lipid-loaded HepG2 cells rewired the hepatic transcriptome profile, with linalool being comparable to those of fenofibrate. Total of 8,988 genes that were commonly and significantly expressed in all experimental groups, including control he...
ORGANISM(S): Homo sapiens 
2013-04-11 | E-GEOD-45961 | biostudies-arrayexpress
TranscriptomicsGlobal hepatic gene expression data from PPARa liver KO, PPARa liver WT, PPARaKO and WT male mice treated or not with Fenofibrate
Fenofibrate is a specific agonist of the nuclear receptor PPARa. To identify the gene expression under the strict dependence of hepatic PPARa activity, we generated a new mouse strain of PPARa-specific deletion in hepatocyte (albumin-Cre+/- Pparaflox/flox or LKO) and we compared them to total Ppara ...
ORGANISM(S): Mus musculus 
2016-02-20 | E-GEOD-73298 | biostudies-arrayexpress
ProteomicsChemoproteomic target deconvolution reveals Histone Deacetylases as targets of (R)-lipoic acid
Chemoproteomic affinity pulldown assays in cancer cell lysates.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-04-20 | MSV000091758 | MassIVE
UnknownTuning of Reciprocal Carbon-Electrode Properties for an Optimized Hydrogen Evolution.
Not available
S-EPMC8252440 | biostudies-literature
TranscriptomicsExpression data from liver, PFC and amygdala of mice treated with PPAR agonists
Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that act as ligand-activated transcription factors. Although prescribed for dyslipidemia and type-II diabetes, PPAR agonists have demonstrated therapeutic properties for several brain disorders, including alcohol depen...
ORGANISM(S): Mus musculus 
2015-04-14 | E-GEOD-67796 | biostudies-arrayexpress
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