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It has been a long debate whether the 98% “non-coding” fraction of human genome can encode functional proteins besides a “random noise” of translation. We used our established translatome sequencing (RNC-seq) to analyze human cells and found that up to 3330 long non-coding RNAs (lncRNAs) were bound ...
ORGANISM(S): Homo Sapiens 
2019-08-29 | PXD044056 |
A Hidden Proteome Encoded by circRNAs in Human Placentas: Implications for Uncovering Preeclampsia Pathogenesis
It has been a long debate whether the 98% “non-coding” fraction of human genome can encode functional proteins besides a “random noise” of translation. We used our established translatome sequencing (RNC-seq) to analyze human cells and found that up to 3330 long non-coding RNAs (lncRNAs) were bound ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-25 | PXD005291 | Pride
Circular RNAs (circRNAs) are consistently overlooked as translational templates due to computational and experimental limitations. Here, we used multi-omics approaches to identify new translational events of circRNAs in human placentas, and assessed the roles of circRNA-encoded proteins in placentat...
ORGANISM(S): Homo sapiens 
2022-02-06 | GSE196032 | GEO
Chloroplast is a major plant cell organelle that fulfills essential metabolic and biosynthetic functions. Located at the interface between the chloroplast and other cell compartments, the chloroplast envelope system is a strategic barrier controlling exchanges of ions, metabolites and proteins, thus...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-04-15 | PXD010545 | Pride
Top-down tissue microproteomic was performed in order to investigate tumoral tissue microenvironment. 289 proteins with post-translational modifications have been isolated from biospies including Tumor, Borderline and healthy regions of serous ovarian cancers. Tumor tissue displays a majority of pro...
ORGANISM(S): Homo sapiens (Human) 
2017-06-23 | PXD005420 | Pride
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