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TranscriptomicsMYBPH, a novel transcriptional target of NKX2-1/TTF-1, inhibits ROCK1 and actomyosin assembly, and reduces cell motility and tumor metastasis
Cell migration driven by actomyosin filament assembly is a critical step in tumour invasion and metastasis. Herein, we report identification of myosin binding protein H (MYBPH) as a transcriptional target of NKX2-1 (also known as TTF-1 and TITF1), a lineage-survival oncogene in lung adenocarcinoma. ...
ORGANISM(S): Homo sapiens 
2011-12-22 | E-GEOD-26721 | biostudies-arrayexpress
TranscriptomicsCodon usage bias is correlated with gene expression levels in the fission yeast Schizosaccharomyces pombe.
Usage of synonymous codons represents a characteristic pattern of preference in each organism. It has been inferred that such bias of codon usage has evolved as a result of adaptation for efficient synthesis of proteins. Here we examined synonymous codon usage in genes of the fission yeast Schizosac...
ORGANISM(S): Schizosaccharomyces pombe 
2010-06-20 | E-GEOD-13554 | biostudies-arrayexpress
UnknownElectron momentum densities near Dirac cones: Anisotropic Umklapp scattering and momentum broadening.
Not available
S-EPMC5428786 | biostudies-literature
UnknownPathway selection in the self-assembly of Rh4L4 coordination squares under kinetic control.
Not available
S-EPMC10651846 | biostudies-literature
TranscriptomicsDistinctive responses to nitrogen starvation in the dominant active mutants of the fission yeast Rheb GTPase.
Rheb, a ras-like small GTPase conserved from human to yeast, controls Tor kinase and plays a central role in regulation of cell growth depending on extracellular conditions. Fission yeast Rheb regulates amino acid uptake as well as response to nitrogen starvation. In this study we generated two muta...
ORGANISM(S): Schizosaccharomyces pombe 
2009-09-28 | E-GEOD-14626 | biostudies-arrayexpress
TranscriptomicsExpression data from epithelial cells during the process of multistep pancreatic carcinogenesis
The host antitumor immunity changes drastically during carcinogenesis. Intraductal papillary-mucinous neoplasm (IPMN) of the pancreas is a precursor lesion of pancreatic cancer and progresses according to adenoma-carcinoma sequence. We found that the host antitumor immune reaction changes from an im...
ORGANISM(S): Homo sapiens 
2010-12-23 | E-GEOD-19650 | biostudies-arrayexpress
UnknownDisordered region of nuclear membrane protein Bqt4 recruits phosphatidic acid to the nuclear envelope to maintain its structural integrity.
Not available
S-EPMC11253665 | biostudies-literature
UnknownAccurate and fiducial-marker-free correction for three-dimensional chromatic shift in biological fluorescence microscopy.
Not available
S-EPMC5954143 | biostudies-literature
ProteomicsAlterations in the sputum proteome and transcriptome in smokers and early-stage COPD patients
Chronic obstructive pulmonary disease (COPD) is one of the most prevalent lung diseases, and involves persistent airflow limitation and incorporates both emphysema and chronic bronchitis. Cigarette smoking has been identified as the main risk factor for disease development and progression. In a basi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-21 | MSV000080275 | MassIVE
UnknownRational design of metal-organic cages to increase the number of components via dihedral angle control.
Not available
S-EPMC11383860 | biostudies-literature
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