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ProteomicsAP-MS analysis of human histone deacetylase interactions in CEM-T cells
Affinity purification-mass spectrometry (AP-MS) datasets of eleven human histone deacetylases (HDACs). Affinity-tagged (GFP) HDACs were expressed in a human CEM-T cell line. For label-free analysis, proteins were digested by trypsin in-solution and peptides separated across a linear 180 min gradient...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-03-07 | MSV000079563 | MassIVE
ProteomicsReader interactome of epigenetic histone marks in birds
Lysine methylation is part of the posttranscriptional histone code employed to recruit modification specific readers to chromatin. Unbiased, quantitative mass spectrometry approaches combined with peptide pull-downs have been used to study histone methylation-dependent binders in mammalian cells. He...
ORGANISM(S): Gallus gallus (Chicken) Taeniopygia guttata (Zebra finch) (Poephila guttata) 
2016-01-04 | PXD002282 | Pride
Histone Birds Lc-msms Interactome 
ProteomicsCFTR interactome
The uploaded files are the RAW files used to generate the CFTR interactome dataset. The raw data were searched with ProLuCID against the human IPI database version 3.23 and search results were filtered with DTASelect 2.1.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-08-13 | MSV000079235 | MassIVE
ProteomicsHistone H3 tail interactome in MPC11 murine myeloma cells
We have used peptide capture in conjunction with super-SILAC quantification to carry out an unbiased high-throughput analysis of the composition of protein complexes that bind to histone H3K9/S10 and H3K27/S28 methyl-phospho modifications. We compared binding profiles of nuclear proteins from MPC11 ...
ORGANISM(S): Mus musculus (Mouse) 
2016-05-04 | PXD001273 | Pride
Lc-msms Histone modification Peptide capture Histone h3 tail interactome 
ProteomicsDevelopment of nucleus-targeted synthetic histone photoaffinity probes
Dissection of the physiological interactomes of histone post-translational modifications (hPTMs) is crucial for understanding fundamental epigenetic regulatory pathways. Current peptide- or protein-based histone photoaffinity probes have greatly expanded the ability to probe the epigenetic interacto...
ORGANISM(S): Mus musculus (Mouse) 
2024-11-21 | PXD045620 | Pride
Nucleus-targeted histone photoaffinity probe Lactylation The epigenetic interactome Hard-to-transfect cells Native cells 
ProteomicsThe functional interactome of site-specifically ubiquitylated linker histone H1
Decoding the role of histone posttranslational modifications (PTMs) is key to understand the fundamental process of epigenetic regulation. While this process is well studied for core histones and many of their PTMs, this is not the case for linker histone H1 in general and its ubiquitylation in part...
ORGANISM(S): Homo sapiens (Human) 
2021-07-20 | PXD020686 | Pride
Epigenetics Linker histone h1 Ubiquitin Posttranslational modification (ptm) Histone code Chromatin 
UnknownDevelopment of nucleus-targeted histone-tail-based photoaffinity probes to profile the epigenetic interactome in native cells.
Not available
S-EPMC11704063 | biostudies-literature
UnknownHistone Monoubiquitination in Chromatin Remodelling: Focus on the Histone H2B Interactome and Cancer.
Not available
S-EPMC7699835 | biostudies-literature
UnknownUncovering the non-histone interactome of the BRPF1 bromodomain using site-specific azide-acetyllysine photochemistry.
Not available
S-EPMC10789646 | biostudies-literature
ProteomicsThe interactome of histone deacetylase HDA19 in dark-grown Arabidopsis seedlings
In this Data Report, we provide an immunoprecipitation (IP)-based analysis of the HDA19 interactome in etiolated Arabidopsis seedlings. We believe that the interactome presented here provides a valuable resource for follow-up research on novel interacting partners of this central protein. The materi...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-09-19 | PXD045454 | Pride
Proteomics Histone acetylation Skotomorphogenesis Etiolated hypocotyl Immunoprecipitation Lc-ms/ms 
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