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Coronaviruses (CoVs) encompass many human pathogens such as HKU-1, OC43, NL63, SARS, MERS and, most recently, nCoV-2019. The spike (S) protein of CoVs has received much attention for its role in host tropism and immunity, but it is becoming increasingly clear that the haemagglutinin esterase (HE) al...
ORGANISM(S): Human coronavirus HKU1 
2020-07-24 | PXD017545 | Pride
Staphylococcus sp. HKU1 Genome sequencing
HKU1 is a human betacoronavirus and infects host cells via highly glycosylated spike protein (S). At present, N-glycosylation of HKU1 S has been reported, however, little is known about its O-glycosylation, which hinders an in-depth understanding of its biological functions. Herein, a comprehensive ...
ORGANISM(S): Human coronavirus HKU1 (isolate N1) 
2022-02-17 | PXD025967 | Pride
Superficieibacter sp. HKU1 isolate:hospitalised patient Genome sequencing
HKU1 isolate in primary cells
Streptococcus pneumoniae strain:HKU1-14 Genome sequencing and assembly
Coronaviruses express a repertoire of accessory proteins for evading host immune responses. A small internal (I) accessory gene overlaps with the nucleocapsid (N) gene in an alternative reading frame of viruses that belong to the genus Betacoronavirus. Previous studies reported that I proteins of SA...
ORGANISM(S): Mus musculus 
2025-04-23 | GSE291309 | GEO
Respiratory organoids enable efficient cultivation of human coronavirus HKU1, elucidation of virus–host interactions and antiviral testing
Heterologous expression of HCoV-HKU1 ORF 7b by mouse hepatitis virus protects against severe disease during murine infection
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