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MetabolomicsSerine and 1-carbon metabolism are required for HIF-mediated protection against retinopathy of prematurity
We determined which metabolic pathways are activated by hypoxia-inducible factor 1-mediated (HIF-1-mediated) protection against oxygen-induced retinopathy (OIR) in newborn mice, the experimental correlate to retinopathy of prematurity, a leading cause of infant blindness. HIF-1 coordinates the chang...
2019-07-05 | MTBLS856 | MetaboLights
ProteomicsNovel role of TrkC in diabetic nephropathy and cross-talk of TrkC with insulin-related signaling
Diabetic nephropathy is a major cause of end-stage renal disease. Kidney podocytes play a central role in the pathogenesis of diabetic nephropathy. With their intercellular contacts they assemble part of the kidney filter. Many molecular mechanisms of the pathogenesis of diabetic nephropathy are not...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-10 | PXD017960 | Pride
Podocyte Mass spectrometry Neurotrophin Ntf3 Trkc Phosphoproteomics Diabetic nephropathy 
UnknownTrkC Is Essential for Nephron Function and Trans-Activates Igf1R Signaling.
Not available
S-EPMC8054883 | biostudies-literature
UnknownRandomized phase 2 trial of regadenoson for treatment of acute vaso-occlusive crises in sickle cell disease.
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S-EPMC5728341 | biostudies-literature
UnknownTraining in the practice of noninvasive brain stimulation: Recommendations from an IFCN committee.
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S-EPMC11624139 | biostudies-literature
UnknownEfficacy and safety of gene therapy with onasemnogene abeparvovec in children with spinal muscular atrophy in the D-A-CH-region: a population-based observational study.
Not available
S-EPMC11492610 | biostudies-literature
UnknownEfficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.
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S-EPMC7787219 | biostudies-literature
UnknownThe effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.
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S-EPMC3145073 | biostudies-literature
UnknownCo-observation of germline pathogenic variants in breast cancer predisposition genes: Results from analysis of the BRIDGES sequencing dataset.
Not available
S-EPMC11393698 | biostudies-literature
UnknownThe impact of coding germline variants on contralateral breast cancer risk and survival.
Not available
S-EPMC10027471 | biostudies-literature
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