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ProteomicsStreamlining of defenses against copper makes host-restricted pathogen reliant on custom-made operon
Copper is both essential and toxic to living beings, which therefore tightly control its intracellular concentration. At the host-pathogen interface, copper is used by phagocytic cells to kill invading microorganisms. We investigated copper homeostasis in the whooping cough agent Bordetella pertussi...
ORGANISM(S): Bordetella bronchiseptica 
2021-09-09 | PXD020900 | Pride
Host-restricted pathogen Oxidative stress Bordetella pertussis Evolution Metallochaperone Copper homeostasis Phagocytosis 
TranscriptomicsMaize tumors caused by Ustilago maydis require organ-specific genes in host and pathogen
Two-organism transcriptome profiling of infected seedling, adult leaf, and tassel demonstrated that both the host and pathogen exhibit organ-specific expression programs. Phenotypic screening of U. maydis mutants deleted for suites of secreted protein genes and maize growth mutants demonstrated org...
ORGANISM(S): Zea mays 
2010-04-01 | E-GEOD-20130 | biostudies-arrayexpress
UnknownRadical genome remodelling accompanied the emergence of a novel host-restricted bacterial pathogen.
Not available
S-EPMC8171923 | biostudies-literature
TranscriptomicsGenome-scale analysis of Staphylococcus aureus reveals host-specific diversification of the core genome.
Staphylococcus aureus causes disease in humans and a wide array of animals. Of note, S. aureus mastitis of ruminants, including cows, sheep and goats, results in major economic losses worldwide. Extensive variation in genome content exists among S. aureus pathogenic clones. However, the genomic vari...
ORGANISM(S): Staphylococcus aureus 
2008-11-18 | E-GEOD-10187 | biostudies-arrayexpress
UnknownHorizontal Gene Acquisitions, Mobile Element Proliferation, and Genome Decay in the Host-Restricted Plant Pathogen Erwinia Tracheiphila.
Not available
S-EPMC4824170 | biostudies-literature
TranscriptomicsMaize tumors caused by Ustilago maydis require organ-specific genes in host and pathogen
Two-organism transcriptome profiling of infected seedling, adult leaf, and tassel demonstrated that both the host and pathogen exhibit organ-specific expression programs. Phenotypic screening of U. maydis mutants deleted for suites of secreted protein genes and maize growth mutants demonstrated orga...
ORGANISM(S): Zea mays Mycosarcoma maydis 
2010-04-01 | GSE20130 | GEO
UnknownParallel evolution of a type IV secretion system in radiating lineages of the host-restricted bacterial pathogen Bartonella.
Not available
S-EPMC3037411 | biostudies-literature
TranscriptomicsMicroarray analysis of defined Mycobacterium tuberculosis populations using RNA amplification strategies
Background The amplification of bacterial RNA is required if complex host-pathogen interactions are to be studied where the recovery of bacterial RNA is limited. Here, using a whole genome Mycobacterium tuberculosis microarray to measure cross-genome representation of amplified mRNA populations, we ...
ORGANISM(S): Mycobacterium tuberculosis 
2008-03-12 | E-BUGS-42 | biostudies-arrayexpress
ProteomicsSecretome Analysis of Mycobacterial-infected Bovine Macrophages
Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, a chronic granulomatous disease. Mtb is mostly restricted to humans and seldom causes disease in animals. M. bovis (Mbv) on the other hand causes tuberculosis in cows (bovine tuberculosis) and several wild animals. Each of thes...
ORGANISM(S): Bos taurus (Bovine) 
2021-03-11 | PXD017949 | Pride
Mycobacterium tuberculosis Bovine macrophages Mycobacterium bovis Host-pathogen interactions Tropism 
TranscriptomicsVaccination against yersiniosis induces a specific gill transcriptome biosignature in Atlantic salmon
Simple cost-effective bacterins are the earliest and most successfully used commercial vaccines in fish. In particular, those prepared from Yersinia ruckeri have proven effective at controlling Enteric Red Mouth Disease (ERM) and yersiniosis in rainbow trout and Atlantic salmon, respectively. Howeve...
ORGANISM(S): Salmo salar 
2012-07-21 | E-GEOD-36332 | biostudies-arrayexpress
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