Programmed death-ligand 1, PD-L1 (CD274) facilitates immune evasion and exerts pro-survival functions in cancer cells. Here, we report a new mechanism whereby internalization of PD-L1 in response to alterations of bioactive lipid/ceramide metabolism by ceramide synthase 4 (CerS4) induces sonic-hedge...
The outer dynein arms (ODAs) are the main force generators in cilia. Crosslinking/mass spectrometry (CLMS) was applied to investigate the interaction between ODA and its binding factor Q22MS1.
