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The activation of dormant primordial follicles is a promising method for rescuing the infertility of aged women and premature ovarian insufficiency (POI) patients. Accumulating evidences in both human and animal suggest that human platelet-rich plasma (hPRP) has the ability to recover ovarian functi...
ORGANISM(S): Mus musculus 
2024-09-01 | GSE263743 | GEO
Fractionation is essential to achieving deep proteome coverage for sample multiplexing experiments where currently up to 18 samples can be analyzed concurrently. However, prefractionation (i.e., upstream of LC-MS/MS analysis) with a liquid chromatography system constrains sample processing as only a...
ORGANISM(S): Homo sapiens (Human) 
2023-12-28 | PXD038383 | Pride
Small, soluble metabolites are not only essential intermediates in intracellular biochemical processes, but can also influence neighboring cells when released into the extracellular milieu. Here, we identify the metabolite and neurotransmitter GABA as a candidate signaling molecule synthesized and s...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-15 | PXD028403 | Pride
Human platelet-rich plasma promotes the primordial follicle activation through the PI3K/Akt signaling pathway
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