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Genomicshspb1
alternative transcript for hspb1
PRJEB43979 | ENA
ProteomicsHDX-MS of HSPB5 and HSPB1 and chimeras
HDX-MS data of HSPB1, HSPB5, and B1/B5 chimeras collected at 4 sec exchange, with fully deuterated, and undeuterated controls.
ORGANISM(S): Homo sapiens (Human) 
2026-09-21 | PXD076277 | Pride
Hspb5 Hspb1 Hdx-ms 
ProteomicsCardiomyocyte-Derived HSPB1 Regulates TGF-β1 Maturation and Inhibits Endothelial-to-Mesenchymal Transition in Myocardial Fibrosis after Infarction
Myocardial fibrosis is a major contributor to heart failure after myocardial infarction (MI), primarily driven by endothelial-to-mesenchymal transition (EndoMT). Heat shock protein B1 (HSPB1) has cardioprotective functions, but its role in MI-induced fibrosis remains unclear. Here, we show that card...
ORGANISM(S): Homo Sapiens 
2025-12-22 | PXD072325 |
GenomicsZKSCAN3 promotes ovarian cancer cell proliferation through upregulating HSPB1
ZKSCAN3 promotes ovarian cancer cell proliferation through upregulating HSPB1
PRJNA1044418 | ENA
GenomicsTargeting HSPB1 Reduces Tumor Growth and Abrogates Treg-Mediated Tumor Immunosuppression
Targeting HSPB1 Reduces Tumor Growth and Abrogates Treg-Mediated Tumor Immunosuppression
PRJNA1306510 | ENA
TranscriptomicsZKSCAN3 promotes ovarian cancer cell proliferation through upregulating HSPB1
Ovarian cancer has the worst prognosis in major gynecological cancers. Current therapies includes platinum, taxol, angiogenesis inhibitor, PARP inhibitor. However, most ovarian cancer patients develop resistance. Identification of more pro-tumor factors in ovarian cancer may shed insight into ovaria...
ORGANISM(S): Homo sapiens 
2025-11-12 | GSE248519 | GEO
TranscriptomicsTargeting HSPB1 Reduces Tumor Growth and Abrogates Treg-Mediated Tumor Immunosuppression
Colorectal cancer (CRC) shows limited responsiveness to immune-checkpoint blockade, highlighting the need for further investigation. The intratumoral Treg/CD8⁺ T-cell ratio serves as a predictive biomarker for therapeutic efficacy. Here, we first demonstrate that targeting HSPB1 lowers this ratio an...
ORGANISM(S): Homo sapiens 
2025-08-20 | GSE305561 | GEO
ProteomicsIdentification of interacting proteins with HSPB1-WT or HSPB1-S3A
IP was performed to identify proteins interacting with HSPB1. Proteins were separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and digested using an in-gel digestion protocol.
ORGANISM(S): Homo Sapiens (human) 
2025-03-07 | PXD050431 | JPOST Repository
UnknownPhosphoserine-86-HSPB1 (pS86-HSPB1) is cytoplasmic and highly induced in rat myometrium at labour.
Not available
S-EPMC9922239 | biostudies-literature
GenomicsHomo sapiens cultivar:cDNA
HSPB1 RNA variants
PRJNA718148 | ENA
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