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ProteomicsHspB8 controls hardening and molecular aging of FUS condensates by domain-specific protein interactions Part 1
Biomolecular condensates formed by phase separation offer a confined space where protein-protein interactions (PPIs) facilitate distinct biochemical reactions. As their aberrant behavior is increasingly associated with disease, it is crucial to understand the molecular organization of PPIs within co...
ORGANISM(S): Homo sapiens (Human) 
2021-10-12 | PXD021114 | Pride
Phase separation Molecular aging Qxl-ms Fus Hspb8 Hsp27 
ProteomicsHspB8 controls molecular aging of FUS condensates by domain-specific protein interactions Part 2
Biomolecular condensates formed by phase separation offer a confined space where protein-protein interactions (PPIs) facilitate distinct biochemical reactions. As their aberrant behavior is associated with disease, it is crucial to understand the molecular organization of PPIs within condensates. Us...
ORGANISM(S): Homo sapiens (Human) 
2021-10-13 | PXD021115 | Pride
Molecular condensates Rrm Protein dynamics Fus Structural proteomics Chaperone Time-resolved quantitative xl-ms Aging 
UnknownCharacterization of Hspb8 in Zebrafish.
Not available
S-EPMC7348923 | biostudies-literature
UnknownMutant HSPB8 causes motor neuron-specific neurite degeneration.
Not available
S-EPMC2908473 | biostudies-literature
UnknownA knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8.
Not available
S-EPMC5756276 | biostudies-literature
UnknownHSPB8 binding to c-Myc alleviates hypoxia/reoxygenation-induced trophoblast cell dysfunction.
Not available
S-EPMC10867730 | biostudies-literature
UnknownRecognition of HSPB8 as a potential therapeutic target for prostate cancer.
Not available
S-EPMC12582549 | biostudies-literature
UnknownHeat shock proteins HSPB8 and DNAJC5B have HCV antiviral activity.
Not available
S-EPMC5705118 | biostudies-literature
UnknownRetinoic Acid Downregulates HSPB8 Gene Expression in Human Breast Cancer Cells MCF-7.
Not available
S-EPMC8201400 | biostudies-literature
UnknownHSPB8 Facilitates the Oncogenesis and Advancement of Bladder Cancer via Activation of HSP27.
Not available
S-EPMC10777032 | biostudies-literature
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