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The tumor microenvironment (TME), which comprises cellular and noncellular components, is involved in the complex process of cancer development. Emerging evidence suggests that mesenchymal stem cells (MSCs), one of the vital regulators of the TME, foster tumor progression through paracrine secretion...
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD029288 | Pride
AnxA4 expression is increased in H. pylori associated tumors. Moreover, in renal-cell cancer, AnxA4 increases tumor cell dissemination and promotes cell migration, and in colorectal cancer, it is identified as a potential diagnostic marker. How AnxA4 might be involved in tumorgenesis has remained un...
ORGANISM(S): Homo sapiens 
We analyzed expression profiles of microRNAs from 22 paired gastric cancer and normal tissues and identified differentially expressed microRNAs. RNA from paired normal and tumor specimens in 22 gastric cancer patients were extracted and treated for microRNA microarray analysis.
ORGANISM(S): Homo sapiens 
AGS cells were treated with metformin then performed iTRAQ proteomics techniques.
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD024996 | Pride
Non-small cell lung cancer is the leading cause of cancer death worldwide. Gefitinib, epidermal growth factor receptor tyrosine kinase inhibitor, is the first-line treatment of NSCLC, however, many patients eventually become resistant and experience progressive disease. Therefore, development of eff...
ORGANISM(S): Homo sapiens (Human) 
2020-08-17 | PXD010767 | Pride
Lung cancer is the leading cause of cancer-related mortality. The two main lung cancer types are small cell lung cancer (SCLC) and non-SCLC (NSCLC), where NSCLC comprises about 80-85% of all lung cancer. Despite the introduction of improved treatments, the overall survival rate of lung cancer patien...
ORGANISM(S): Homo sapiens (Human) 
2018-10-26 | PXD003743 | Pride
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