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UnknownThe Spin-Orbit Effect on the Electronic Structures, Refractive Indices, and Birefringence of X2PO4I (X = Pb, Sn, Ba and Sr): A First-Principles Investigation.
Not available
S-EPMC11013657 | biostudies-literature
MetabolomicsThe telomere-to-telomere (T2T) genome of Peucedanum praeruptorum Dunn provides insights into the genome evolution and coumarin biosynthesis

BACKGROUND: Traditional Chinese medicine has used Peucedanum praeruptorum Dunn (Apiaceae) for a long time. Various coumarins, including the significant root constituents Praeruptorin (A-E), are the active constituents of the dried roots of P. praeruptorum. Previous trans...

2024-04-02 | MTBLS8679 | MetaboLights
ProteomicsHuman Cell 293T BCAT1 IP GC-LC-MS
To identify the potential interaction protein that interacts with BCAT1 by IP-MS, we established the stable cell line with vector and BCAT1 in AGS. Then ten million cells were collected lysed in ice-cold 0.1% NP-40 buffer (50 mM Na2HPO4, pH 7.5, 150 mM NaCl) with protease inhibitors cocktail (Sigma,...
ORGANISM(S): Homo sapiens (Human) 
2024-11-15 | PXD041556 | Pride
Huamn bcat1 ip-ms 
ProteomicsCalpain-mediated Protein Targets in Cardiac Mitochondria following Ischemia-Reperfusion
Calpain 1 and 2 (CPN1/2) are calcium-dependent cysteine proteases that exist in cytosol and mitochondria. Pharmacologic inhibition of CPN1/2 decreases cardiac injury during ischemia (ISC) – reperfusion (REP) by improving mitochondrial function. However, the protein targets of CPN1/2 activation durin...
ORGANISM(S): Mus musculus (Mouse) 
2021-12-21 | PXD022689 | Pride
Calpain  mitochondrial respiratory chain  reactive oxygen species Reverse electron flow 
MetabolomicsThe Toxoplasma micropore mediates endocytosis for selective nutrient salvage from host cell compartments

Apicomplexan parasite growth and replication relies on nutrient acquisition from host cells, in which intracellular multiplication occurs, yet the mechanisms that underlie the nutrient salvage remain elusive. Numerous ultrastructural studies have documented a plasma membrane invagination with a d...

2023-04-19 | MTBLS7006 | MetaboLights
ProteomicsME1 Interaction in HEK293T CELLS
To search potential interaction with ME1 in HEK293T cells under different conditions
ORGANISM(S): Homo sapiens (Human) 
2026-05-18 | PXD077606 | Pride
Hek293t 
ProteomicsER-associated degradation ligase HRD1 links ER stress to DNA damage repair by modulating the activity of DNA-PKcs
ER-associated degradation ligase HRD1 links ER stress to DNA damage repair by modulating the activity of DNA-PKcs
ORGANISM(S): Homo Sapiens 
2024-08-20 | PXD055020 |
ProteomicsPhosphoproteomic profiling of Neospora caninum tachyzoites and PKG inhibitor MBP146-78 treatment
In this study, phosphorylation levels of Neospora caninum parasite (Nc1 strains) tachyzoites were compared with PKG inhibitor MBP146-78 treated and untreated, contains two replicates. Therefore, four subprojects are included in this project. Subproject IPX0011618001 is composed of the sub-dataset ge...
ORGANISM(S): Neospora Caninum 
2025-04-09 | PXD062765 |
ProteomicsTargeting RANKL-Independent Osteoclastogenesis Overcomes Denosumab Resistance in ER+ Breast Cancer Bone Metastasis
Bone metastasis remains a major cause of morbidity in ER+ breast cancer, with RANKL inhibitor resistance emerging as a critical clinical challenge. Nearly 40% of patients develop progressive skeletal lesions despite denosumab therapy, highlighting an urgent need to identify resistance mechanisms and...
ORGANISM(S): Homo Sapiens 
2026-01-29 | PXD073739 |
ProteomicsTargeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
The efficacy of immunotherapy against colorectal cancer (CRC) is impaired by insufficient immune cell recruitment into the tumor microenvironment. Our study shows that targeting circDNA2v, a circular RNA commonly overexpressed in CRC, can be exploited to elicit cytotoxic T-cell recruitment. CircDNA2...
ORGANISM(S): Homo Sapiens 
2024-04-11 | PXD051359 |
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