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TranscriptomicsCXCL12/CXCR4 signaling mediates niche occupancy and tumor maintenance in T-cell leukemia
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy characterized by infiltration of the bone marrow and other sites with transformed T cell progenitors. The role of tissue microenvironments in the pathogenesis of T-ALL or any other type of acute leukemia is little ...
ORGANISM(S): Mus musculus 
2015-08-12 | E-GEOD-60367 | biostudies-arrayexpress
UnknownPatients with lung cancer and paraneoplastic Hu syndrome harbor HuD-specific type 2 CD8+ T cells.
Not available
S-EPMC2701858 | biostudies-literature
UnknownNon-contrast computed tomography characteristics in a large cohort of cystinuria patients.
Not available
S-EPMC8332560 | biostudies-literature
TranscriptomicsGenome-wide localization of Ino80 on chromosome in Saccharomyces cerevisiae
Background: Chromatin remodeling complexes facilitate the access of enzymes that mediate transcription, replication or repair of DNA by modulating nucleosome position and/or composition. Ino80 is the DNA-dependent Snf2-like ATPase subunit of a complex whose nucleosome remodeling activity requires ac...
ORGANISM(S): Saccharomyces cerevisiae 
2008-04-10 | E-GEOD-9420 | biostudies-arrayexpress
TranscriptomicsGenome-wide localization of Ino80 and Arp5 on chromosome in Saccharomyces cerevisiae
Background: Chromatin remodeling complexes facilitate the access of enzymes that mediate transcription, replication or repair of DNA by modulating nucleosome position and/or composition. Ino80 is the DNA-dependent Snf2-like ATPase subunit of a complex whose nucleosome remodeling activity requires ac...
ORGANISM(S): Saccharomyces cerevisiae 
2008-04-10 | E-GEOD-9233 | biostudies-arrayexpress
UnknownMicroRNA-29 regulates T-box transcription factors and interferon-γ production in helper T cells.
Not available
S-EPMC3361370 | biostudies-literature
UnknownBach2 Negatively Regulates T Follicular Helper Cell Differentiation and Is Critical for CD4+ T Cell Memory.
Not available
S-EPMC6504585 | biostudies-literature
UnknownPerforin-dependent CD4+ T-cell cytotoxicity contributes to control a murine poxvirus infection.
Not available
S-EPMC3382508 | biostudies-literature
TranscriptomicsGlobal Target mRNA Specification and Regulation by RNA-Binding Protein ZFP36/Tristetraprolin/TTP [PAR-CLIP]
Tristetraprolin/ZFP36/TTP and ELAVL1/HuR are two disease-relevant RNA-binding proteins (RBPs) that both interact with AU-rich sequences but have antagonistic roles. While ELAVL1 binding has been profiled in several studies, the precise in vivo binding specificity of ZFP36 has not been investigated o...
ORGANISM(S): Homo sapiens 
2013-12-24 | E-GEOD-53184 | biostudies-arrayexpress
TranscriptomicsE.coli MG1655M-NM-^T6/pCA24N-dinJ treated with erythromycin vs. MG1655M-NM-^T6/pCA24N
Antitoxins are becoming recognized as proteins that regulate more than their own synthesis; for example, we found previously that antitoxin MqsA represses the gene encoding the stationary phase sigma factor RpoS. Here, we investigated the physiological role of antitoxin DinJ of the DinJ/YafQ toxin/a...
ORGANISM(S): Escherichia coli 
2012-07-08 | E-GEOD-30692 | biostudies-arrayexpress
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