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Manganese (Mn), an essential element for plants, can be toxic when present in excess. Stylo (Stylosanthes) is a pioneer tropical legume with great potential for Mn tolerance, but its Mn tolerance mechanisms remain poorly understood. In this study, the mechanisms underlying stylo response to Mn toxic...
ORGANISM(S): Stylosanthes guianensis 
2019-05-06 | PXD012379 | Pride
To identify which E3 ligases ubiquitinate PD-L1, we overexpressed PD-L1-Flag in HEK293 cells and used anti-Flag magnetic beads to pull down PD-L1 from cell lysates. The interacting proteins were then analyzed by mass spectrometry, revealing that three E3 ligases interact with PD-L1.
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD057691 | Pride
To elucidate which secreted factors in tumor tissues (TTs) are responsible for the upregulation of UBE4A as the tumor progresses, we inoculated tumors in mice and analyzed the 2- and 4-week TT fluid by mass spectrometry (MS). By combining molecular weight cut off(MWCO) and the identification of secr...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD058079 | Pride
Staphylococcus aureus (S. aureus), a major cause of hospital and community-acquired pneumonia, still has a high mortality rate. Extracellular vesicles (EVs), as crucial mediators of intercellular communication, have a significant impact on infectious diseases. However, the role of EVs from alveolar ...
ORGANISM(S): Mus Musculus 
2024-05-21 | PXD052452 |
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