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UnknownAdjuvant heparanase inhibitor PI-88 therapy for hepatocellular carcinoma recurrence.
Not available
S-EPMC4145780 | biostudies-literature
ProteomicsIdentification of miR-16/29 targets in adipocytes by LC-MSMS
Cancer cachexia is a multifactorial metabolic syndrome defined by the rapid loss of skeletal muscle mass and the loss of fat mass. Up 80% of cancer patients at the late stage with cachexia suffer from progressive atrophy of adipose tissue. Unlike studies on skeletal muscle wasting, there is limited ...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-13 | PXD037998 | Pride
Lc-msms Mouse Adipocytes Mirnas 
ProteomicsIdentification of miR-16/29 targets in adipocytes by LC-MSMS
Cancer cachexia is a multifactorial metabolic syndrome defined by the rapid loss of skeletal muscle mass and the loss of fat mass. Up 80% of cancer patients at the late stage with cachexia suffer from progressive atrophy of adipose tissue. Unlike studies on skeletal muscle wasting, there is limited ...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-13 | PXD037862 | Pride
Lc-msms Mouse Adipocytes Mirnas 
TranscriptomicsComparative transcriptome analysis of Gastrodia elata (Orchidaceae) in response to fungus symbiosis to identify gastrodin biosynthesis-related genes
Gastrodia elata Blume (Orchidaceae) is an important Chinese medicine with several functional components. In the life cycle of G. elata, the orchid develops a symbiotic relationship with two compatible mycorrhizal fungi Mycena spp. and Armillaria mellea during seed germination to form vegetative prop...
ORGANISM(S): Gastrodia elata 
2016-08-23 | E-GEOD-73633 | biostudies-arrayexpress
ProteomicsN-Glycosylation-Defective IL6 Alternatively Activates the SRC-YAP-SOX2 Axis to Drive Metastasis and EGFR TKI Resistance
The IL6-GP130-STAT3 pathway facilitates lung cancer progression and resistance to tyrosine kinase inhibitors. Although glycosylation alters the stability of GP130, its effect on the ligand IL6 remains unclear. We herein found that N-glycosylated IL6, especially at Asn73, primarily stimulates JAK-STA...
ORGANISM(S): Homo sapiens (Human) 
2025-01-18 | PXD051771 | Pride
Il6  glycosylation  lung cancer  emt  metastasis  egfr-tki resistance  src  yap 
MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
UnknownTargeting CAR and Nrf2 improves cyclophosphamide bioactivation while reducing doxorubicin-induced cardiotoxicity in triple-negative breast cancer treatment.
Not available
S-EPMC9309041 | biostudies-literature
UnknownComparing Low- or Standard-Dose Alteplase in Endovascular Thrombectomy: Insights From a Nationwide Registry.
Not available
S-EPMC10896194 | biostudies-literature
UnknownDelayed production of neutralizing antibodies correlates with fatal COVID-19.
Not available
S-EPMC8785364 | biostudies-literature
UnknownDe novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.
Not available
S-EPMC7007577 | biostudies-literature
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