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TranscriptomicsExpression analysis of C. elegans wild-type N2 and rsks-1, daf-2, daf-2 rsks-1 and daf-16; daf-2 rsks-1 mutants
Investigation of whole genome gene expression level changes in C. elegans rsks-1, daf-2, daf-2 rsks-1 and daf-16; daf-2 rsks-1 mutant compared to the wild-type N2 strain. The mutants have altered longevity phenotypes. The mutants analyzed in this study are further described in Di Chen, Patrick Wai-...
ORGANISM(S): Caenorhabditis elegans 
2013-11-14 | E-GEOD-52340 | biostudies-arrayexpress
TranscriptomicsExpression analysis of C. elegans wild-type N2 and rsks-1, daf-2, daf-2 rsks-1 and daf-16; daf-2 rsks-1 mutants
Investigation of whole genome gene expression level changes in C. elegans rsks-1, daf-2, daf-2 rsks-1 and daf-16; daf-2 rsks-1 mutant compared to the wild-type N2 strain. The mutants have altered longevity phenotypes. The mutants analyzed in this study are further described in Di Chen, Patrick Wai-L...
ORGANISM(S): Caenorhabditis elegans 
2013-11-14 | GSE52340 | GEO
TranscriptomicsGene expression on 144 arrays representing 125 workers exposed to a range of benzene exposures
Human toxicogenomic studies to date have been of limited size, have mainly addressed exposures at the upper end of typical ranges of human exposure, and have often lacked precise, individual estimates of exposure. Previously, we identified genes associated with exposure to high (>10 ppm) levels of t...
ORGANISM(S): Homo sapiens 
2011-05-14 | E-GEOD-21862 | biostudies-arrayexpress
TranscriptomicsEccentric exercise activates novel transcriptional regulation of hypertrophic signaling pathways
Full title: Eccentric exercise activates novel transcriptional regulation of hypertrophic signaling pathways not affected by hormone changes. Unaccustomed eccentric exercise damages muscle tissue stimulating mechanisms of recovery and remodeling that may be affected by cellular protection by the sex...
ORGANISM(S): Homo sapiens 
2009-12-16 | E-GEOD-19062 | biostudies-arrayexpress
TranscriptomicsInsulin-like Signaling Determines Survival During Stress via Post Transcriptional Mechanisms in C. elegans.
The insulin-like signaling (ILS) pathway regulates metabolism and is known to modulate adult lifespan in C. elegans. Altered stress responses and resistance to a wide range of stressors are also associated with changes in ILS and contribute to enhanced longevity. The transcription factors DAF-16 and...
ORGANISM(S): Caenorhabditis elegans 
2010-06-17 | E-GEOD-22383 | biostudies-arrayexpress
TranscriptomicsFunctional profiling in yeast with the benzene metabolites hydroquinone, catechol and 1,2,4-benzenetriol
Benzene is a ubiquitous environmental contaminant and is widely used in industry. Exposure to benzene causes a number of serious health problems, including blood disorders and leukemia. Benzene undergoes complex metabolism in humans, making mechanistic determination of benzene toxicity difficult. We...
ORGANISM(S): Saccharomyces cerevisiae 
2013-03-13 | E-GEOD-45116 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of amino-acid starved yeast cells to monitor the transcript level and also the translation status for each RNA
Global restriction of protein synthesis is a hallmark of cellular stress. Using amino-acid starvation, we monitor the transcript level and also the translation status for each RNA using cycloheximide to freeze elongating ribosomes. Polyribosome fractionation of cell extracts was used to seperate hig...
ORGANISM(S): Saccharomyces cerevisiae 
2005-10-01 | E-MEXP-323 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of butanol treated yeast to monitor the transcript level and also the translation status for each RNA
Global restriction of protein synthesis is a hallmark of cellular stress. Using fusel alchohol addition, we monitor the transcript level and also the translation status for each RNA using cycloheximide to freeze elongating ribosomes. Polyribosome fractionation of cell extracts was used to seperate h...
ORGANISM(S): Saccharomyces cerevisiae 
2005-10-01 | E-MEXP-324 | biostudies-arrayexpress
TranscriptomicsMassage therapy attenuates NFκB nuclear accumulation and inflammatory cytokine production following damage in human skeletal muscle
Massage therapy is commonly used for the physical rehabilitation of skeletal muscle to ameliorate pain and promote recovery from injury. While there is some evidence that massage may relieve pain in injured muscle, the cellular effects remain unknown. To assess the effects of massage, we administer...
ORGANISM(S): Homo sapiens 
2011-11-10 | E-GEOD-33603 | biostudies-arrayexpress
GenomicsCaenorhabditis elegans
Expression analysis of C. elegans wild-type N2 and rsks-1, daf-2, daf-2 rsks-1 and daf-16 daf-2 rsks-1 mutants
PRJNA227451 | ENA
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