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ProteomicsTranslationalLandscape_HumanHeart
Here, we analyze the expression of predicted microproteins in human heart tissue and iPSC cardiomyocytes, using shot-gun proteomics and SRM. 4 identified candidates were functionally validated by interactome studies using AP-MS (affinity purification coupled to mass spectrometry). In addition, the i...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2019-06-04 | PXD012593 | Pride
Shot gun Heart tissue Targeted proteomics 
TranscriptomicsTranscription profiling of SBH/y rats vs SBN/y rats under basal conditions and after salt loading
Gene expression was studied in whole kidneys in a 2 x 2 design. SBH/y were contrasted with SBN/y under basal conditions and after salt loading. Thus, four groups were studied altogether. Five rats were used in each group. Altogether, 20 animals were used, and each animal was studied separately. G...
ORGANISM(S): Rattus norvegicus 
2004-09-10 | E-MEXP-157 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of gonads from E14.5 megalin+/+ and megalin-/- embryos
Presently, genes regulated by steroid hormones during induced regression of the CSL (cranial suspensory ligament) are unknown. To identify such genes and to evaluate their expression levels in megalin-deficient mice, we performed global gene expression profiling on gonads from E14.5 megalin+/+ and m...
ORGANISM(S): Mus musculus 
2005-06-30 | E-MEXP-352 | biostudies-arrayexpress
GenomicsDAC for Cardiac Translatomes of 80 Human Samples (65 DCM cases 15 controls)
Data Access Committee EGAC00001001040
EGAC00001001040 | EGA
TranscriptomicsTranscription profiling of mouse embryonic stem cell line CGR8 grown in presence of Leukemia Inhibitory Factor and treated with trichostatin A
This experiment is part of the FunGenES project (FunGenES - Functional Genomics in Embryonic Stem Cells partially funded by the 6th Framework Programme of the European Union, http://www.fungenes.org). The experiment was conducted at the Institute for Molecular Biology and Biotechnology FORTH, Herakl...
ORGANISM(S): Mus musculus 
2009-07-10 | E-TABM-670 | biostudies-arrayexpress
TranscriptomicsFungenES: FunGenES_UKOE-4: Functional characterization and transcriptome analysis of embryonic stem cells-derived contractile smooth muscle cells
This experiment is part of the FunGenES project (FunGenES - Functional Genomics in Embryonic Stem Cells partially funded by the 6th Framework Programme of the EuropeanUnion, http://www.fungenes.org). The experiment was conducted at University of Cologne, Cologne, Germany. Goal of the experiment is a...
ORGANISM(S): Mus musculus 
2011-02-25 | E-TABM-1123 | biostudies-arrayexpress
OtherQuantitative interaction proteomics of neurodegenerative disease proteins.
Data from ProteomeXchange, PXD ID: PXD001942. File: 20130829_Orbi6_FaHo_SA_NN_SWEvsEV_Rep3_01.mzml. Published as part of Cell Rep. 2015 May 19;11(7):1134-46 . From the Abstract: {{i}} Several proteins have been linked to neurodegenerative disorders (NDDs), but their molecular function is not comple...
ORGANISM(S): Homo_sapiens_viruses, Human_female 
GPM32320018141 | GPMDB
Resource Reanalysis 
TranscriptomicsFunGenES: UED-LF2: HOXB4 can enhance the differentiation of embryonic stem cells by modulating the haematopoietic niche
Haematopoietic differentiation of embryonic stem (ES) cells in vitro has been used as a model to study early haematopoietic development and it is well documented that haematopoietic differentiation can be enhanced by over-expression of HOXB4. HOXB4 is expressed in haematopoietic progenitor cells (HP...
ORGANISM(S): Mus musculus 
2011-02-05 | E-MTAB-547 | biostudies-arrayexpress
GenomicsNatural variation of histone modification and its impact on gene expression in rat
Histone modifications are epigenetic marks that play fundamental roles in many biological processes including the control of chromatin-mediated regulation of gene expression. To begin to understand the impact of natural variation on histone methylation levels we generated and quantified large-scale ...
ORGANISM(S): Rattus norvegicus 
2012-05-30 | E-MTAB-1102 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of peritoneal fat of SHR/01a (spontaneously hypertensive rat), BN-Lx (Brown Norway congenic carrying polydactyly-luxate syndrome)and recombinant inbred (HXB/BXH) 6-week old rat strains
Gene expression profiling of peritoneal fat of SHR/01a (spontaneously hypertensive rat), BN-Lx (Brown Norway congenic carrying polydactyly-luxate syndrome)and recombinant inbred (HXB/BXH) 6-week old rat strains.
ORGANISM(S): Rattus norvegicus 
2010-11-18 | E-AFMX-7 | biostudies-arrayexpress
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