Sort   by:  
 Page size 
GenomicsHigh-Resolution Nucleosome Mapping Reveals Transcription-Dependent Promoter Packaging
Genome-wide mapping of nucleosomes has revealed a great deal about the relationships between chromatin structure and control of gene expression, and has led to mechanistic hypotheses regarding the rules by which chromatin structure is established. High-throughput sequencing has recently become the t...
ORGANISM(S): Saccharomyces cerevisiae 
2009-10-15 | E-GEOD-18530 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Mycobacterium tuberculosis to analyse the regulatory role of the HigA antitoxin
Data is also available from BuG@Sbase
ORGANISM(S): Mycobacterium tuberculosis 
2010-07-16 | E-BUGS-107 | biostudies-arrayexpress
UnknownRisk of marrow neoplasms after adjuvant breast cancer therapy: the national comprehensive cancer network experience.
Not available
S-EPMC4302215 | biostudies-literature
TranscriptomicsMulti-tissue gene expression profiles of human brain (CR)
The genetics of complex disease produce alterations in molecular interactions of cellular pathways which collective effect may become clear through the organized structure of molecular networks. To characterize molecular systems associated with late-onset Alzheimer´s disease (LOAD), we constructed g...
ORGANISM(S): Homo sapiens 
2013-04-25 | E-GEOD-44768 | biostudies-arrayexpress
TranscriptomicsMulti-tissue gene expression profiles of human brain (PFC)
The genetics of complex disease produce alterations in molecular interactions of cellular pathways which collective effect may become clear through the organized structure of molecular networks. To characterize molecular systems associated with late-onset Alzheimer´s disease (LOAD), we constructed g...
ORGANISM(S): Homo sapiens 
2013-04-25 | E-GEOD-44770 | biostudies-arrayexpress
TranscriptomicsMulti-tissue gene expression profiles of human brain (VC)
The genetics of complex disease produce alterations in molecular interactions of cellular pathways which collective effect may become clear through the organized structure of molecular networks. To characterize molecular systems associated with late-onset Alzheimer´s disease (LOAD), we constructed g...
ORGANISM(S): Homo sapiens 
2013-04-25 | E-GEOD-44771 | biostudies-arrayexpress
TranscriptomicsRNAseq of tumor samples from CT26 syngeneic mouse treated with a PD-L1 and CTLA-4 immunotherapy combination
The ability to modulate immune-inhibitory pathways using checkpoint blockade antibodies such as PD-1, PD-L1, and CTLA-4 represents a significant breakthrough in cancer therapy in recent years. This has driven interest in identifying small-molecule-immunotherapy combinations to increase the proportio...
ORGANISM(S): Mus musculus 
2020-04-16 | E-MTAB-7777 | biostudies-arrayexpress
ProteomicsA quantitative proteomics approach to monitor targeted protein degradation in M. smegmatis
Targeted protein degradation via the ubiquitin proteasome has been established in eukaryotes, however no application has been shown in bacteria so far. In the present work, selective protein degradation is shown using hetero bifunctional drugs, bringing substrates in close proximity to the bacterial...
ORGANISM(S): Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Bacteria 
2022-08-12 | PXD021505 | Pride
Mycobacteria Targeted protein degradation Protease Tpd 
GenomicsGenome-wide maps of nucleosome positions in Saccharomyces strains bearing heterologous DNA on yeast artificial chromosomes
We identify the cis and trans determinants of nucleosome positioning using a functional evolutionary approach involving S. cerevisiae strains containing large genomic regions from other yeast species. In a foreign species, nucleosome depletion at promoters is maintained over poly(dA:dT) tracts, wher...
ORGANISM(S): Saccharomyces cerevisiae 
2012-06-30 | E-GEOD-39011 | biostudies-arrayexpress
ProteomicsIsolation method and characterization of outer membranes vesicles of Helicobacter pylori grown in a chemically defined medium
Outer membrane vesicles (OMVs) are small vesicles constitutively shed by all Gram-negative bacterium, which have been proposed to play a role in Helicobacter pylori persistence and pathogenesis. The methods currently available for the isolation of H. pylori OMVs are diverse and time-consuming, raisi...
ORGANISM(S): Helicobacter pylori 26695 
2021-05-31 | PXD025393 | Pride
Proteomics Helicobacter pylori Bacterial outer membrane vesicles Bacteria viability Defined medium Isolation protocol 
Sort   by:  
 Page size