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TranscriptomicsIdentification of miR-21 targets in Jurkat cells by AGO2 immunoprecipitation
In order to identify miR-21 targets by a biochemical high-throughput method, we immunopurified RISC Complex and associated mRNAs in both control and miR-21 overexpressing Jurkat cells. Following transduction of miR-21 encoding construct (or a cognate control vector) in Jurkat cells, we used microarr...
ORGANISM(S): Homo sapiens 
2014-10-15 | E-GEOD-37212 | biostudies-arrayexpress
ProteomicsHuman Jurkat T cells SENP1 immunoprecipitates LC-MS
Identification of peptides matching to LCK in SENP1 immunoprecipitates from Jurkat E6.1 T cells by mass spectrometry
ORGANISM(S): Homo sapiens (Human) 
2022-01-13 | PXD029720 | Pride
Human Senp1 Lc-ms Jurkat t cells 
TranscriptomicsExpression data from human Jurkat T cells exposed to 31 compounds
Compounds with direct immunotoxic properties, including metals, mycotoxins, agricultural pesticides and industrial chemicals, form potential human health risks due to exposure through food, drinking water, and the environment. Insights into the mechanisms of action are currently lacking for the majo...
ORGANISM(S): Homo sapiens 
2013-07-22 | E-GEOD-46909 | biostudies-arrayexpress
MetabolomicsIdentification of AK4 and RHOC as novel oncogenes addicted by adult T-cell leukemia
Adult T-cell leukemia (ATL) is a highly aggressive T-cell malignancy characterized by human T-cell leukemia virus type 1 (HTLV-1) infection. ATL has a very poor prognosis and lacks satisfactory treatments; therefore, it is critical to identify novel targets in ATL cells in order to develop effective...
2025-02-03 | MTBLS11844 | MetaboLights
TranscriptomicsTranscription profiling by array of human PMA-activated Jurkat cells
Cyclin T1-dependent genes in activated Jurkat cells. HIV-1 is dependent upon cellular co-factors to mediate its replication cycle in CD4+ T cells and macrophages, the two major cell types infected by the virus in vivo. One critical co-factor is Cyclin T1, a subunit of a general RNA polymerase II el...
ORGANISM(S): Homo sapiens 
2008-10-20 | E-GEOD-10232 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human T cell leukaemia cell line Jurkat that were retrovirally transduced with constitutievely active forms of Notch to identify novel transcriptional targets of Notch signalling
In this study we aimed to identify novel transcriptional targets of Notch signalling in the T cell leukaemia cell line, Jurkat. RNA was prepared from Jurkat cells retrovirally transduced with an empty vector (Mock) or vectors containing constitutively active forms of Notch (N1deltaE or N3deltaE), an...
ORGANISM(S): Homo sapiens 
2009-07-15 | E-MEXP-1744 | biostudies-arrayexpress
GenomicsGenome-wide binding map of the HIV Tat protein to the human genome (ChIP-Seq)
The HIV-1 Trans-Activator of Transcription (Tat) protein binds to multiple host cellular factors and greatly enhances the level of transcription of the HIV genome. Here, we report the genome-wide binding map of Tat to the human genome in Jurkat T cells (Jurkat-Tat cells) using chromatin immunopreci...
ORGANISM(S): Homo sapiens 
2011-11-06 | E-GEOD-30738 | biostudies-arrayexpress
ProteomicsHuman Jurkat T cells Lck-immunoprecipitates LC-MS
Identification of peptides matching to CEP83 in Lck immunoprecipitates from Jurkat T cells by mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2026-09-27 | PXD078925 | Pride
Human Lc-ms Lck Jurkat t cells 
TranscriptomicsFOXP3 binding sites in promoter regions of human Jurkat T cells
The transcription factor (TF) Forkhead Box P3 (FOXP3) is constitutively expressed in high levels in natural occurring CD4+CD25+ regulatory T cells (nTreg) and is not only the most accepted marker for that cell population, but is considered lineage determinative. Chromatin immunoprecipitation (ChIP) ...
ORGANISM(S): Homo sapiens 
2012-11-26 | E-GEOD-37252 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression profiles of HIV-specific CD8 T cells from controllers and progressors and Jurkat cells with or without PD-1 ligation
This SuperSeries is composed of the following subset Series: GSE24026: Comparison of gene expression profiles of Jurkat cells with or without PD-1 ligation GSE24081: Comparison of gene expression profiles of HIV-specific CD8 T cells from controllers and progressors Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-10-03 | E-GEOD-24082 | biostudies-arrayexpress
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