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TranscriptomicsmiRNAs high throughput sequencing profiling of regenerating human airway epithelial cells
The regeneration of the airway mucociliary epithelium involves several sequential events including migration, proliferation, polarization and final differentiation (i.e ciliogenesis). The airway mucociliary epithelium is consituted of three main cell types : ciliated cells, secretory cells and basal...
ORGANISM(S): Homo sapiens 
2011-06-06 | E-GEOD-22144 | biostudies-arrayexpress
UnknownGeneration of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells.
Not available
S-EPMC4035971 | biostudies-literature
ProteomicsDNAAF9 interactome from human airway epithelial cells
Biogenesis of motile cilia in multiciliated cells (MCCs) is coupled to large-scale biosynthesis of force generating dynein motors. Shulin inhibits pre-assembled ODA (outer dynein arm) motors by packaging them into a closed conformation preventing aberrant off-target interactions with cellular microt...
ORGANISM(S): Homo sapiens (Human) 
2025-07-31 | PXD052722 | Pride
Lc-msms Axonemal dyneins Dnaaf Tmt Human multiciliated airway cells 
TranscriptomicsMicroRNA signature during the time course of regeneration of the human airway mucociliary epithelium
The regeneration of the airway mucociliary epithelium involves several sequential events including migration, proliferation, polarization and final differentiation (i.e ciliogenesis). The airway mucociliary epithelium is consituted of three main cell types : ciliated cells, secretory cells and basal...
ORGANISM(S): Homo sapiens 
2011-06-06 | E-GEOD-22141 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis during the time course of regeneration of the human airway mucociliary epithelium
The regeneration of the airway mucociliary epithelium involves several sequential events including migration, proliferation, polarization and final differentiation (i.e ciliogenesis). We used microarrays to detail the global programme of gene expression that occurs during regeneration and ciliogenes...
ORGANISM(S): Homo sapiens 
2011-06-06 | E-GEOD-22142 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA sequencing of CellTagging lung organoids
Here, we used a lentiviral-based barcoding method (CellTagging) to lineage trace progenitor cells in a human lung organoid model. 21-day cultures were transduced for 7 days, fluorescence activated cell sorted for GFP+ expression, and regrown as sparsely plated cells for additional 30 days before seq...
ORGANISM(S): Homo sapiens 
2023-04-21 | E-MTAB-12753 | biostudies-arrayexpress
UnknownRegionally distinct progenitor cells in the lower airway give rise to neuroendocrine and multiciliated cells in the developing human lung.
Not available
S-EPMC10268599 | biostudies-literature
UnknownProminin 1 and Notch regulate ciliary length and dynamics in multiciliated cells of the airway epithelium.
Not available
S-EPMC9356082 | biostudies-literature
TranscriptomicsSingle-cell RNA sequencing reveals deuterosomal cells during differentiation of hiPSCs into airway multiciliated cells
We performed single-cell RNA sequencing (scRNA-seq) to investigate the differentiation of human induced pluripotent stem cells (hiPSCs) into airway multiciliated cells. The analysis revealed diverse epithelial cell types, including basal, secretory, goblet, and pulmonary neuroendocrine cells, as wel...
ORGANISM(S): Homo sapiens 
2026-03-19 | GSE299245 | GEO
GenomicsDerivation of airway basal stem cells from human pluripotent stem cells
Derivation of airway basal stem cells from human pluripotent stem cells
PRJNA596381 | ENA
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