Sort   by:  
 Page size 
ProteomicsCharacterization of Early-Phase Neutrophil Extracellular Traps in Urinary Tract Infections
Neutrophils have an important role in rapid antimicrobial defenses against and resolution of urinary tract infections (UTIs). We show that a mechanism known as neutrophil extracellular trap (NET) formation is a strategy to combat pathogens in the urinary tract. Viscous aggregates that were present i...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080847 | MassIVE
TranscriptomicsNeutrophil-derived pro-inflammatory cytokine response and degranulation in function of time and dose of LPS treatment.
The purpose of the present study was to elucidate in more details the molecular mechanisms of neutrophil-mediated inflammation. We therefore investigated the time-dependent stimulatory potential of LPS from Escherichia coli on cytokine response in neutrophil-like HL-60 cells.

To get a genera...
ORGANISM(S): Homo sapiens 
2014-12-17 | E-MTAB-1393 | biostudies-arrayexpress
TranscriptomicsCritical COPD respiratory illness is linked to increased transcriptomic activity of neutrophil proteases genes.
Abstract
BACKGROUND: Gene expression profiling (GEP) in cells obtained from peripheral blood has demonstrated to be a very useful approach for biomarker discovery and for studying molecular pathogenesis of prevalent diseases. While there is limited literature availble on gene expression markers a...
ORGANISM(S): Homo sapiens 
2013-03-12 | E-MEXP-3589 | biostudies-arrayexpress
ProteomicsThe Miniaturized Isolation of Neutrophil Granules (MING) method allowed a deep proteome mapping of human neutrophil granules
Search files, Raw mass spectrum files in a non-standard (.raw) and standardized format (.mzML) for shotgun proteomics of the neutrophil granules using the MING method.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-08-24 | MSV000095691 | MassIVE
ProteomicsProteome profiling of human neutrophil granule subsets, secretory vesicles, and cell membrane
In the present work neutrophil subcellular fractionation by density gradient centrifugation was conducted in order to perform a quantitative proteomic profiling of human neutrophil granule subsets, secretory vesicles, and cell membrane
ORGANISM(S): Homo sapiens (Human) 
2017-06-23 | PXD005559 | Pride
Lc-msms Quantitative proteomic profiling Secretory vesicles Human neutrophil granules 
ProteomicsSpatiotemporal glycoproteome remodelling in neutrophils
Neutrophils are short-lived yet vital innate immune cells equipped with bioactive glycoproteins packed in cytosolic granules that can readily be mobilised to elicit an effective and timely response against invading pathogens. Since the dynamic glycosylation processes underpinning the dramatic metamo...
ORGANISM(S): Homo sapiens (Human) 
2023-09-18 | PXD039387 | Pride
Remodelling Neutrophil Glycoproteomics Maturation Granule Glycoproteome 
UnknownGlycan analysis of human neutrophil granules implicates a maturation-dependent glycosylation machinery.
Not available
S-EPMC7476722 | biostudies-literature
TranscriptomicsTracking the Fragile X Mental Retardation Protein in a Highly Ordered Neuronal RiboNucleoParticles Population: a Link Between Stalled Polyribosomes and RNA Granules
Local translation at the synapse plays key roles in neuron development and activity-dependent synaptic plasticity. mRNAs are translocated from the neuronal soma to the distant synapses as compacted ribonucleoparticles referred to as RNA granules. These contain many RNA-binding proteins, including th...
ORGANISM(S): Mus musculus 
2016-06-30 | E-GEOD-83835 | biostudies-arrayexpress
ProteomicsNeutrophil specific granule and NETosis defect in Gray Platelet Syndrome
Gray Platelet Syndrome (GPS) is an autosomal recessive bleeding disorder characterized by a lack of α-granules in platelets and progressive myelofibrosis. Rare loss of function variants in NBEAL2, a member of the family of BEACH genes, are causal of GPS. The gene is involved in fusion, fission and t...
ORGANISM(S): Homo sapiens (Human) 
2021-01-28 | PXD017784 | Pride
Neutrophil Gray platelet syndrome 
UnknownIdentification of a Novel Splice Variant Isoform of TREM-1 in Human Neutrophil Granules.
Not available
S-EPMC4670805 | biostudies-literature
Sort   by:  
 Page size