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ProteomicsQuantitative Live Cell Imaging Reveals Differential Manipulation of Rab11A Transport Pathways by Influenza virus and RSV
Assembly of infectious influenza A viruses (IAV) is a complex process involving transport from the nucleus to the plasma membrane. Rab11A containing recycling endosomes have been identified as a platform for intracellular transport of viral RNA (vRNA). Using high spatiotemporal resolution light-shee...
ORGANISM(S): Homo sapiens (Human) Influenza A virus (A/California/07/2009(H1N1)) 
2020-01-14 | PXD016331 | Pride
Live-cell imaging Rab11a Influenza virus Vesicle tracking Light-sheet microscopy Assembly Rna Microtubules Endosomes Fluorescence microscopy Viral rna Motor transport 
ProteomicsPlasma membrane proteome of adhesion-competent endometrial epithelial cells and its modulation by Rab11a
Human endometrial epithelium (EE) is composed of a multitude of proteins, amongst which those localized on the plasma membrane (plasma membrane proteins-PMPs) are of critical relevance in early stages of implantation. Evidences support the key role of few PMPs in implantation. However, many remain u...
ORGANISM(S): Homo sapiens (Human) 
2019-11-08 | PXD015010 | Pride
Epithelium Plasma membrane Ishikawa Proteomics Endometrium 
ProteomicsInteractome analysis of human Rab11a with proteins from influenza A virus infected cell lysates
The aim of this project was to determine which viral and host proteins bind to purified recombinant human GTPase Rab11a from lysates of HEK-293T cells infected with influenza A/WSN/33 (H1N1) virus. To this aim we used a GST pull-down assay. Approximately 8∙106 HEK-293T cells were infected with influ...
ORGANISM(S): Homo sapiens (Human) Influenza A virus (A/WSN/1933(H1N1)) 
2022-01-17 | PXD030058 | Pride
Influenza virus infection Interactome Human rab11a 
ProteomicsRab11a and Rab11b immunoprecipitates
We want to determine the protein networks that are associated with Rab11a and Rab11b, individually. We performed immunoprecipitation against Flag-tagged Rab11a or Flag-tagged Rab11b in HEK293 cells, and subjected the immunoprecipitates to mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2023-06-05 | PXD042300 | Pride
Rab11 
ProteomicsAccessory ESCRT-III proteins are conserved and selective regulators of Rab11a-exosome formation
Exosomes are secreted nanovesicles with potent signalling activity that are initially formed as intraluminal vesicles (ILVs) in late Rab7-positive multivesicular endosomes, and also in recycling Rab11a-positive endosomes, particularly under some forms of nutrient stress. The core proteins of the En...
ORGANISM(S): Homo sapiens (Human) 
2024-08-02 | PXD040361 | Pride
Escrt/ chmp5/ extracellular vesicle/ rab11a-exosome/ recycling endosome 
GenomicsNext Generation Sequencing Facilitates Quantitative Analysis of Control siRNA, RAB11A siRNA1 and RAB11A siRNA2 suppressed EBC-1 cell's Transcriptomes
Next Generation Sequencing Facilitates Quantitative Analysis of Control siRNA, RAB11A siRNA1 and RAB11A siRNA2 suppressed EBC-1 cell's Transcriptomes
PRJNA739983 | ENA
TranscriptomicsNext Generation Sequencing Facilitates Quantitative Analysis of Control siRNA, RAB11A siRNA1 and RAB11A siRNA2 suppressed EBC-1 cell's Transcriptomes
This study aims to find cellular pathway changes in RAB11A suppressed in lung squamous cell carcinoma cell line EBC-1 compared to control and to evaluate downregulating genes by RAB11A suppression by siRNA. Total RNA was extracted from EBC-1 transfected with control siRNA and RAB11A specific siRNAs ...
ORGANISM(S): Homo sapiens 
2021-06-23 | GSE178669 | GEO
ProteomicsThe Viral Polymerase Complex Mediates the Interaction of vRNPs with Recycling Endosomes During SeV Assembly
Paramyxoviruses are negative sense single-stranded RNA viruses that comprise many important human and animal pathogens, including human parainfluenza viruses. These viruses bud from the plasma membrane of infected cells after the viral ribonucleoprotein complex (vRNP) is transported from the cytopla...
ORGANISM(S): Homo sapiens (Human) Murine respirovirus 
2020-08-06 | PXD019637 | Pride
Rab11a Sendai virus cantell A549 cells 
UnknownRab11a regulates syntaxin 3 localization and microvillus assembly in enterocytes.
Not available
S-EPMC4518445 | biostudies-literature
UnknownRab11a and myosin Vb are required for bile canalicular formation in WIF-B9 cells.
Not available
S-EPMC1257697 | biostudies-literature
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