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Background: Rotator cuff tear (RCT) is a prevalent shoulder injury, and postoperative exercise is considered to facilitate RCT healing. However, the effect of postoperative exercise on RCT healing through gut microbiota and metabolites remains unclear.

Method: The control (con) group (n=10...

2026-03-03 | MTBLS13894 | MetaboLights
Sjogren’s syndrome (SS) is characterized by dysfunctional mucous membranes and dysregulated moisture-secreting glands resulting in various symptoms, including dry mouth and dry eyes. Here, we wanted to profile and compare the tears and saliva proteomes of SS patients to healthy controls. Tear and sa...
ORGANISM(S): Homo sapiens (Human) 
2021-10-04 | PXD028922 | Pride
Several proteomics studies have been conducted to identify new cerebrospinal fluid (CSF) biomarkers in Multiple Sclerosis (MuS). However, the complexity of CSF and its invasive collection, limits its use. Therefore, the goal of biomarker research in MuS is to identify novel distinctive targets in CS...
ORGANISM(S): Homo sapiens (Human) 
2019-06-06 | PXD013794 | Pride
Rotator cuff tears are one of the most common shoulder disorders and can lead to pain, weakness, and limited mobility. Although the clinical condition has been widely studied, its molecular mechanisms are still not fully understood. In this study, we analyzed the proteomic profile of synovial fluid ...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD064264 | Pride
RNA-Seq analysis of traumatic and degenerative tears of tendon tissues of human shoulder joint
RNA-Seq analysis of traumatic and degenerative tears of subacromial bursal tissues of human shoulder joint
“Dry eye” is a multi-factorial inflammatory disease affecting the ocular surface. Tear hyperosmolarity in dry eye contributes to inflammation and cell damage. Recent research efforts on dry eye have been directed towards biomarker discovery for diagnosis, response to treatment and disease mechanisms...
2015-08-31 | MTBLS214 | MetaboLights
Thyroid-Associated Orbitopathy (TAO) is an autoimmune inflammatory disease that affects the eye. To date, this pathology is not very well characterised and the diagnosis remains sometimes quite challenging. The aim of this study was to try to discover in tears of TAO patients some potential biomarke...
ORGANISM(S): Homo sapiens (Human) 
2017-10-04 | PXD006871 | Pride
The anterior cruciate ligament (ACL) is an essential stabilizer of the tibiofemoral articulation. ACL tears often lead to functional instability and are associated with an increased risk for osteoarthritis. The healing potential of the injured ACL is poorly understood and is considered to be limited...
ORGANISM(S): Homo sapiens 
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