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TranscriptomicsFunGenES: UED-LF2: HOXB4 can enhance the differentiation of embryonic stem cells by modulating the haematopoietic niche
Haematopoietic differentiation of embryonic stem (ES) cells in vitro has been used as a model to study early haematopoietic development and it is well documented that haematopoietic differentiation can be enhanced by over-expression of HOXB4. HOXB4 is expressed in haematopoietic progenitor cells (HP...
ORGANISM(S): Mus musculus 
2011-02-05 | E-MTAB-547 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse embyronic stem cells cultured with PI3-K signalling inhibitor LY294002 to identify PI3K-target genes
This experiment is part of the FunGenES project (FunGenES - Functional Genomics in Embryonic Stem Cells partially funded by the 6th Framework Programme of the European Union, http://www.fungenes.org).The experiment was conducted at the Unyversity of Bath, Bath, UK. Aim of the experiment is the ident...
ORGANISM(S): Mus musculus 
2009-05-07 | E-TABM-673 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse wild type R1 and cells expressing Pax4 following induction of pacreatic differentitation
This experiment is part of the FunGenES project (FunGenES - "Functional Genomics in Embryonic Stem Cells" partially funded by the 6th Framework Programme of the European Union, http://www.fungenes.org). The experiment was conducted at the Leibniz Institute of Plant Genetics and Crop Plant Research (...
ORGANISM(S): Mus musculus 
2009-03-01 | E-TABM-493 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse embyronic stem cells cultured with PI3-K signalling inhibitor LY294002 for different lengths of time to identify PI3K-target genes
This experiment is part of the FunGenES project (FunGenES - Functional Genomics in Embryonic Stem Cells partially funded by the 6th Framework Programme of the European Union, http://www.fungenes.org).The experiment was conducted at the Unyversity of Bath, Bath, UK. Aim is to identify genes regulated...
ORGANISM(S): Mus musculus 
2009-05-07 | E-TABM-674 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse embryonic stem cells in vitro - FunGenES: IMM-1: Neural Differentiation of Embryonic Stem Cells in vitro: a Road Map to Neurogenesis in the Embryo
This experiment is part of the FunGenES project (FunGenES - "Functional Genomics in Embryonic Stem Cells" partially funded by the 6th Framework Programme of the European Union, http://www.fungenes.org). The experiment was conducted at the "Instituto de Medicina Molecular,Faculdade de Medicina de Lis...
ORGANISM(S): Mus musculus 
2009-07-23 | E-TABM-717 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse embryonic stem cells to identify genes regulated by STAT3 and NANOG, known differentiation inhibitors
This experiment is part of the FunGenES project (FunGenES - Functional Genomics in Embryonic Stem Cells partially funded by the 6th Framework Programme of the European Union, http://www.fungenes.org). The experiment was conducted at the Inst. National de la Santé et de la Recherche Médicale - INS ...
ORGANISM(S): Mus musculus 
2009-03-01 | E-TABM-562 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat heart from Lewis strain immunized with a peptide of human alpha1A-adrenergic receptor
Gene expression profiles in hearts of Lewis rats immunized with a peptide of human alpha1A-adrenergic receptor. The pathophysiological relevance of chronic autoantibodies against alpha-1A-adrenergic receptor stimulation in rats was investigated. Lewis rats were immunized using synthesized peptides o...
ORGANISM(S): Rattus norvegicus 
2010-06-15 | E-TABM-725 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse embryonic stem cell line CGR8 treated with Leukemia Inhibitory Factor (LIF) to identify LIF-dependent genes and early differentiation markers
This experiment is part of the FunGenES project (FunGenES - Functional Genomics in Embryonic Stem Cells partially funded by the 6th Framework Programme of the European Union, http://www.fungenes.org). The experiment was conducted at the University Bordeaux 2 (CNRS UMR 5164). The purpose of the exper...
ORGANISM(S): Mus musculus 
2009-07-10 | E-TABM-667 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of spontaneously hypertensive heart failure rats (SHHF) and a reference strain to identify heart failure susceptibility genes
We aimed to identify gene variants associated with heart failure by using a rat model of the human disease. We performed invasive cardiac hemodynamic measurements in F2 crosses between spontaneously hypertensive heart failure rats (SHHF) and reference strains. We combined linkage analyses with genom...
ORGANISM(S): Rattus norvegicus 
2008-09-01 | E-TABM-418 | biostudies-arrayexpress
MetabolomicsAutomated Label-free Quantification of Metabolites from Liquid Chromatography–Mass Spectrometry Data (Simulated)

Liquid chromatography coupled to mass spectrometry (LC-MS) has become a standard technology in metabolomics. In particular, label-free quantification based on LC-MS is easily amenable to large-scale studies and thus well suited to clinical metabolomics. Large-scale studies, however, require autom...

2015-12-16 | MTBLS235 | MetaboLights
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