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TranscriptomicsDissecting the signalling pathways underlying cellular senescence
Cellular senescence is a program of irreversible cell cycle arrest that normal cells undergo in response to progressive shortening of telomeres, changes in telomeric structure, oncogene activation or oxidative stress. The underlying signalling pathways, potentially of major clinicopathological rele...
ORGANISM(S): Homo sapiens 
2011-01-21 | E-GEOD-24810 | biostudies-arrayexpress
UnknownA Copine family member, Cpne8, is a candidate quantitative trait gene for prion disease incubation time in mouse.
Not available
S-EPMC2854345 | biostudies-literature
UnknownA 7.5 Mb sequence-ready PAC contig and gene expression map of human chromosome 11p13-p14.1.
Not available
S-EPMC310838 | biostudies-literature
TranscriptomicsSuppression of p53-mediated senescence by non-canonical NF-kappaB pathway mediated regulation of EZH2 expression
The NF-kappaB and p53 transcription factors control the expression of complex gene regulatory networks in response to many cell stresses and stimuli. This experiment describes gene expression profiling of cells depleted for EZH2, NF-kappaB2, RelB and p53. We find that EZH2 is the major effector of c...
ORGANISM(S): Homo sapiens 
2014-03-31 | E-MTAB-1593 | biostudies-arrayexpress
UnknownGANESH: software for customized annotation of genome regions.
Not available
S-EPMC403729 | biostudies-literature
UnknownSimultaneous expression of MMB-FOXM1 complex components enables efficient bypass of senescence.
Not available
S-EPMC8563780 | biostudies-literature
UnknownGenetic analysis of the cytoplasmic dynein subunit families.
Not available
S-EPMC1331979 | biostudies-literature
UnknownActivation of nuclear factor-kappa B signalling promotes cellular senescence.
Not available
S-EPMC3080811 | biostudies-literature
UnknownInherited mtDNA variations are not strong risk factors in human prion disease.
Not available
S-EPMC6542657 | biostudies-literature
UnknownHECTD2 is associated with susceptibility to mouse and human prion disease.
Not available
S-EPMC2633041 | biostudies-literature
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