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HUVEC were treated with 3 mM (pH=7.4) as the high concentration of phosphorus (HP) and normal phosphorus (NP) for exosomes concentration. The HUVEC-Exos samples (HP: 3 samples, NP: 3 samples) were processed for label-free-based quantitative proteomic analysis using high-performance liquid chromatogr...
ORGANISM(S): Homo Sapiens 
2022-09-21 | PXD036925 |
Next-generation sequencing analyzes EPC-drived exosome miRNA content and alterations of mRNA expression in exosomes treated HUVEC
mRNA expression of HUVEC cells treated by exosomes derived from colorectal cancer cell line HCT116 transfected with lncRNA-APC1 silenced or control vector
Purpose: To dissect the mechanisms of EPC-drived exosome in promoting endothelial cells reendothelialization, next-generation sequencing was used to determine exosome miRNA content and alterations in mRNA expression in HUVEC. Methods: The miRNA of EPC-drived exosomes sequencing was carried out on th...
ORGANISM(S): Homo sapiens 
2022-01-03 | GSE124692 | GEO
Rhabdomyosarcoma (RMS) is a highly malignant soft tissue sarcoma classified into two major histologic subtypes: embryonal (ERMS) and alveolar (ARMS). ARMS subtype is clinically more aggressive, and characterized by an oncogenic fusion protein PAX3-FOXO1 (P3F) that drives oncogenic cellular propertie...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-08 | PXD017543 | Pride
The expression profile of HUVEC in response to IgG or HECD-1 treated exosomes We used data from this array to identify differentiatly expressed genes.
ORGANISM(S): Homo sapiens 
2017-02-23 | GSE95174 | GEO
To determine the mRNA expression profile of HUVEC cells treated by exosomes derived from colorectal cancer cell line HCT116 transfected with lncRNA-APC1 silenced or control vector, we performedd gene expression microArray analysis form Arraystar to examine the expression of mRNAs.
ORGANISM(S): Homo sapiens 
2019-02-07 | GSE113739 | GEO
Intercellular communication is critical for integrating complex signals in multicellular eukaryotes. Vascular endothelial cells and T lymphocytes closely interact during the recirculation and trans-endothelial migration of T cells. In addition to direct cell-cell contact, we show that T cell deriv...
ORGANISM(S): Homo sapiens 
Recently, the existence of extracellular miRNAs enclosed in exosomes has raised the possibility that they play an important role in cell-cell communication. To gain more insight into cell-cell communication via exosomal miRNAs, we investigated whether or not tumor cells exposed to hypoxia secrete ex...
ORGANISM(S): Homo sapiens 
Recently, the existence of extracellular miRNAs enclosed in exosomes has raised the possibility that they play an important role in cell-cell communication. To gain more insight into cell-cell communication via exosomal miRNAs, we investigated whether or not tumor cells exposed to hypoxia secrete ex...
ORGANISM(S): Homo sapiens 
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