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Preterm prelabour rupture of membranes (PPROM) complicated by intra-amniotic inflammation (IAI) represents a substantial portion of preterm birth cases. Currently, IAI is frequently defined as amniotic fluid IL-6 concentration above 2600 pg/mL However, the amniotic fluid IL-6 concentration was never...
ORGANISM(S): Homo sapiens (Human) 
2025-04-30 | PXD057800 | Pride
Using RNA-sequencing (RNA-Seq and miRNA-Seq), we analyzed paired villous trophoblast and decidual basalis transcriptomes of 15 women pregnant with singleton gestations grouped as follows: (1) spontaneous preterm birth (PTB) in the setting of amniocentesis-proven intra-amniotic infection (IAI) and hi...
ORGANISM(S): Homo sapiens 
Using RNA-sequencing (RNA-Seq and miRNA-Seq), we analyzed paired villous trophoblast and decidual basalis transcriptomes of 15 women pregnant with singleton gestations grouped as follows: (1) spontaneous preterm birth (PTB) in the setting of amniocentesis-proven intra-amniotic infection (IAI) and hi...
ORGANISM(S): Homo sapiens 
Intra-amniotic infection (IAI) is associated with substantial maternal and neonatal risks, yet the immunoregulatory role of the human placenta remains incompletely understood. We established an in vitro IAI model by co-culturing term human placental explants with lipopolysaccharide (LPS) and monitor...
ORGANISM(S): Homo sapiens 
2025-11-28 | GSE310377 | GEO
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